Development of a Low-Cost Gastroscope Prototype (GP) for Potential Cost-Effective Gastric Cancer Screening in Prevalent Regions
Background Screening for gastric cancer is known to be associated with reduced mortality in populations with high prevalence. However, many countries with high prevalence do not screen, with high costs being a significant reason for this. Aims To describe, develop, and assess the potentia...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2023-03-01
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| Series: | Journal of Digestive Endoscopy |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1762574 |
| _version_ | 1827976790300164096 |
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| author | James Xu Mark E. Benson Liam M. Granlund Seth Gehrke Dylan Stanfield Jennifer Weiss Patrick Pfau Anurag Soni Ben L. Cox George Petry Robert A. Swader Mark Reichelderfer Zhanhai Li Tenzin Atrukstang Nyah Banik Kevin W. Eliceiri Deepak V. Gopal |
| author_facet | James Xu Mark E. Benson Liam M. Granlund Seth Gehrke Dylan Stanfield Jennifer Weiss Patrick Pfau Anurag Soni Ben L. Cox George Petry Robert A. Swader Mark Reichelderfer Zhanhai Li Tenzin Atrukstang Nyah Banik Kevin W. Eliceiri Deepak V. Gopal |
| author_sort | James Xu |
| collection | DOAJ |
| description | Background Screening for gastric cancer is known to be associated with reduced mortality in populations with high prevalence. However, many countries with high prevalence do not screen, with high costs being a significant reason for this.
Aims To describe, develop, and assess the potential for a low-cost gastroscope for early cancer screening and patient risk stratification.
Methods Our interdisciplinary team used both off-the-shelf and fabricated components to create multiple gastroscope prototypes (GP) in iterative fashion based off clinician feedback. Clinician endoscopists were surveyed using Likert scales regarding device potential, video quality, and handling when testing on a GI training device. Video quality comparison to clinically standard high-definition white light endoscopy (HD-WLE) was done using the absolute categorical ratings (ACR) method.
Results A candidate cost-effective GP with clinical potential was developed. Although initial versions were scored as inferior via ACR on all views tested when compared to HD-WLE (p < 0.001), participants agreed the concept may be beneficial (M = 4.52/5, SD = 0.72). In testing improved versions, participants agreed the device had the ability to identify discrete (M = 4.62/5, SD = 0.51) and subtle lesions (M = 4/5, SD = 0.7) but most felt video quality, although improved, was still less than HD-WLE. Sufficiency of maneuverability of device to visualize gastric views was rated as equivocal (M = 2.69/5, SD = 1.25).
Conclusion The presented low-cost gastroscopic devices have potential for clinical application. With further device development and refinement including the possible addition of technologies in telemedicine and artificial intelligence, we hope the GP can help expand gastric cancer screening for populations in need. |
| first_indexed | 2024-04-09T20:41:03Z |
| format | Article |
| id | doaj.art-48bdfba84ff4421580660c0854370e6a |
| institution | Directory Open Access Journal |
| issn | 0976-5042 0976-5050 |
| language | English |
| last_indexed | 2024-04-09T20:41:03Z |
| publishDate | 2023-03-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Journal of Digestive Endoscopy |
| spelling | doaj.art-48bdfba84ff4421580660c0854370e6a2023-03-30T00:12:48ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Digestive Endoscopy0976-50420976-50502023-03-01140102202910.1055/s-0043-1762574Development of a Low-Cost Gastroscope Prototype (GP) for Potential Cost-Effective Gastric Cancer Screening in Prevalent RegionsJames Xu0Mark E. Benson1Liam M. Granlund2Seth Gehrke3Dylan Stanfield4Jennifer Weiss5Patrick Pfau6Anurag Soni7Ben L. Cox8George Petry9Robert A. Swader10Mark Reichelderfer11Zhanhai Li12Tenzin Atrukstang13Nyah Banik14Kevin W. Eliceiri15Deepak V. Gopal16Division of Gastroenterology & Hepatology, Department of Medicine, University of Wisconsin School of Medicine & Public Health, Wisconsin, United StatesDivision of Gastroenterology & Hepatology, Department of Medicine, University of Wisconsin School of Medicine & Public Health, Wisconsin, United StatesMorgridge Institute for Research, Madison, Wisconsin, United StatesMorgridge Institute for Research, Madison, Wisconsin, United StatesDivision of Gastroenterology & Hepatology, Department of Medicine, University of Wisconsin School of Medicine & Public Health, Wisconsin, United StatesDivision of Gastroenterology & Hepatology, Department of Medicine, University of Wisconsin School of Medicine & Public Health, Wisconsin, United StatesDivision of Gastroenterology & Hepatology, Department of Medicine, University of Wisconsin School of Medicine & Public Health, Wisconsin, United StatesDivision of Gastroenterology & Hepatology, Department of Medicine, University of Wisconsin School of Medicine & Public Health, Wisconsin, United StatesMorgridge Institute for Research, Madison, Wisconsin, United StatesMorgridge Institute for Research, Madison, Wisconsin, United StatesMorgridge Institute for Research, Madison, Wisconsin, United StatesDivision of Gastroenterology & Hepatology, Department of Medicine, University of Wisconsin School of Medicine & Public Health, Wisconsin, United StatesDepartment of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, Wisconsin, United StatesDivision of Gastroenterology & Hepatology, Department of Medicine, University of Wisconsin School of Medicine & Public Health, Wisconsin, United StatesDivision of Gastroenterology & Hepatology, Department of Medicine, University of Wisconsin School of Medicine & Public Health, Wisconsin, United StatesMorgridge Institute for Research, Madison, Wisconsin, United StatesDivision of Gastroenterology & Hepatology, Department of Medicine, University of Wisconsin School of Medicine & Public Health, Wisconsin, United StatesBackground Screening for gastric cancer is known to be associated with reduced mortality in populations with high prevalence. However, many countries with high prevalence do not screen, with high costs being a significant reason for this. Aims To describe, develop, and assess the potential for a low-cost gastroscope for early cancer screening and patient risk stratification. Methods Our interdisciplinary team used both off-the-shelf and fabricated components to create multiple gastroscope prototypes (GP) in iterative fashion based off clinician feedback. Clinician endoscopists were surveyed using Likert scales regarding device potential, video quality, and handling when testing on a GI training device. Video quality comparison to clinically standard high-definition white light endoscopy (HD-WLE) was done using the absolute categorical ratings (ACR) method. Results A candidate cost-effective GP with clinical potential was developed. Although initial versions were scored as inferior via ACR on all views tested when compared to HD-WLE (p < 0.001), participants agreed the concept may be beneficial (M = 4.52/5, SD = 0.72). In testing improved versions, participants agreed the device had the ability to identify discrete (M = 4.62/5, SD = 0.51) and subtle lesions (M = 4/5, SD = 0.7) but most felt video quality, although improved, was still less than HD-WLE. Sufficiency of maneuverability of device to visualize gastric views was rated as equivocal (M = 2.69/5, SD = 1.25). Conclusion The presented low-cost gastroscopic devices have potential for clinical application. With further device development and refinement including the possible addition of technologies in telemedicine and artificial intelligence, we hope the GP can help expand gastric cancer screening for populations in need.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1762574endoscopygastric cancerscreening |
| spellingShingle | James Xu Mark E. Benson Liam M. Granlund Seth Gehrke Dylan Stanfield Jennifer Weiss Patrick Pfau Anurag Soni Ben L. Cox George Petry Robert A. Swader Mark Reichelderfer Zhanhai Li Tenzin Atrukstang Nyah Banik Kevin W. Eliceiri Deepak V. Gopal Development of a Low-Cost Gastroscope Prototype (GP) for Potential Cost-Effective Gastric Cancer Screening in Prevalent Regions Journal of Digestive Endoscopy endoscopy gastric cancer screening |
| title | Development of a Low-Cost Gastroscope Prototype (GP) for Potential Cost-Effective Gastric Cancer Screening in Prevalent Regions |
| title_full | Development of a Low-Cost Gastroscope Prototype (GP) for Potential Cost-Effective Gastric Cancer Screening in Prevalent Regions |
| title_fullStr | Development of a Low-Cost Gastroscope Prototype (GP) for Potential Cost-Effective Gastric Cancer Screening in Prevalent Regions |
| title_full_unstemmed | Development of a Low-Cost Gastroscope Prototype (GP) for Potential Cost-Effective Gastric Cancer Screening in Prevalent Regions |
| title_short | Development of a Low-Cost Gastroscope Prototype (GP) for Potential Cost-Effective Gastric Cancer Screening in Prevalent Regions |
| title_sort | development of a low cost gastroscope prototype gp for potential cost effective gastric cancer screening in prevalent regions |
| topic | endoscopy gastric cancer screening |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1762574 |
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