Pairwise association of upper extremity musculoskeletal conditions: large population investigation from PERSIAN cohort study
Abstract Background People with one area of upper extremity musculoskeletal conditions (UEMSCs) may have other. We aim to determine how frequent is the ipsilateral coexistence of common UEMSCs apparent on interview and examination. Methods This is a large population cross-sectional study conducted a...
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| Format: | Article |
| Language: | English |
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BMC
2023-08-01
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| Series: | Journal of Orthopaedic Surgery and Research |
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| Online Access: | https://doi.org/10.1186/s13018-023-04108-6 |
| _version_ | 1827633675900026880 |
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| author | Mahla Daliri Farideh Khosravi Mohammad-T. Shakeri Mohammad H Ebrahimzadeh Ali Moradi |
| author_facet | Mahla Daliri Farideh Khosravi Mohammad-T. Shakeri Mohammad H Ebrahimzadeh Ali Moradi |
| author_sort | Mahla Daliri |
| collection | DOAJ |
| description | Abstract Background People with one area of upper extremity musculoskeletal conditions (UEMSCs) may have other. We aim to determine how frequent is the ipsilateral coexistence of common UEMSCs apparent on interview and examination. Methods This is a large population cross-sectional study conducted as part of the PERSIAN cohort study int Mashhad University of Medical Sciences (MUMS). The study aimed to evaluate individuals for symptoms and signs of the following conditions: carpal tunnel syndrome (CTS), lateral epicondylitis (LE), trapeziometacarpal osteoarthritis (TMC OA), DeQuervain’s tendinopathy, trigger digit (TD), ganglion cyst, and rotator cuff tendinopathy (RCT). The primary outcomes of the study are (1) to determine the side-specific relative risk of each UEMSC coexisting with the second condition, and (2) to identify predictive factors of each UEMSC using side-specific multivariate logistic regression analysis. Results We conducted a study involving 4737 individuals from the staff of MUMS and found significant pairwise associations among UEMSCs on a side-specific basis. Women had more chance of having DeQuervain’s disease (β = 6.3), CTS (β = 3.5), ganglion cyst (β = 2.5), TMC OA (β = 2.3), and RCT (β = 2.0). Each condition (dependent variable) was associated with others (predictors) as follows: CTS: RCT (β = 5.9), TMC OA (β = 4.7), TD (β = 2.9), and LE (β = 2.5). TMC OA: LE (β = 6.4), TD (β = 5.4), RCT (β = 4.3), and CTS (β = 4.1). LE: RCT (β = 8.1), TMC OA (β = 6.4), and CTS (β = 2.5). DeQuervain’s disease: TD (β = 13.6), RCT (β = 4.5), and LE (β = 3.8). TD: CTS (β = 8.8), ganglion cyst (β = 7.6), DeQuervain’s disease (β = 5.7), and TMC OA (β = 4.3). RCT: LE (β = 5.8), TMC OA (β = 5.5), CTS (β = 5.2), and DeQuervain’s disease (β = 4.3). Ganglion cyst: TD (β = 4.8). Conclusion Our study reports significant increased frequency of the UEMSCs among patients who already have one of the diseases, in a large sample size study. Level of Evidence Level II (Differential Diagnosis/Symptom Prevalence Study). |
| first_indexed | 2024-03-09T15:02:51Z |
| format | Article |
| id | doaj.art-48c208413bb54c8686c675a804783aac |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-03-09T15:02:51Z |
| publishDate | 2023-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-48c208413bb54c8686c675a804783aac2023-11-26T13:48:03ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2023-08-011811910.1186/s13018-023-04108-6Pairwise association of upper extremity musculoskeletal conditions: large population investigation from PERSIAN cohort studyMahla Daliri0Farideh Khosravi1Mohammad-T. Shakeri2Mohammad H Ebrahimzadeh3Ali Moradi4Orthopedics Research Center, Ghaem Hospital, Mashhad University of Medical SciencesStudent Research Committee, School of Health, Mashhad University of Medical SciencesDepartment of Biostatistics, Mashhad University of Medical SciencesOrthopedics Research Center, Ghaem Hospital, Mashhad University of Medical SciencesOrthopedics Research Center, Ghaem Hospital, Mashhad University of Medical SciencesAbstract Background People with one area of upper extremity musculoskeletal conditions (UEMSCs) may have other. We aim to determine how frequent is the ipsilateral coexistence of common UEMSCs apparent on interview and examination. Methods This is a large population cross-sectional study conducted as part of the PERSIAN cohort study int Mashhad University of Medical Sciences (MUMS). The study aimed to evaluate individuals for symptoms and signs of the following conditions: carpal tunnel syndrome (CTS), lateral epicondylitis (LE), trapeziometacarpal osteoarthritis (TMC OA), DeQuervain’s tendinopathy, trigger digit (TD), ganglion cyst, and rotator cuff tendinopathy (RCT). The primary outcomes of the study are (1) to determine the side-specific relative risk of each UEMSC coexisting with the second condition, and (2) to identify predictive factors of each UEMSC using side-specific multivariate logistic regression analysis. Results We conducted a study involving 4737 individuals from the staff of MUMS and found significant pairwise associations among UEMSCs on a side-specific basis. Women had more chance of having DeQuervain’s disease (β = 6.3), CTS (β = 3.5), ganglion cyst (β = 2.5), TMC OA (β = 2.3), and RCT (β = 2.0). Each condition (dependent variable) was associated with others (predictors) as follows: CTS: RCT (β = 5.9), TMC OA (β = 4.7), TD (β = 2.9), and LE (β = 2.5). TMC OA: LE (β = 6.4), TD (β = 5.4), RCT (β = 4.3), and CTS (β = 4.1). LE: RCT (β = 8.1), TMC OA (β = 6.4), and CTS (β = 2.5). DeQuervain’s disease: TD (β = 13.6), RCT (β = 4.5), and LE (β = 3.8). TD: CTS (β = 8.8), ganglion cyst (β = 7.6), DeQuervain’s disease (β = 5.7), and TMC OA (β = 4.3). RCT: LE (β = 5.8), TMC OA (β = 5.5), CTS (β = 5.2), and DeQuervain’s disease (β = 4.3). Ganglion cyst: TD (β = 4.8). Conclusion Our study reports significant increased frequency of the UEMSCs among patients who already have one of the diseases, in a large sample size study. Level of Evidence Level II (Differential Diagnosis/Symptom Prevalence Study).https://doi.org/10.1186/s13018-023-04108-6Carpal tunnel syndromeLateral epicondylitisMusculoskeletalPairwise associationUpper extremity |
| spellingShingle | Mahla Daliri Farideh Khosravi Mohammad-T. Shakeri Mohammad H Ebrahimzadeh Ali Moradi Pairwise association of upper extremity musculoskeletal conditions: large population investigation from PERSIAN cohort study Journal of Orthopaedic Surgery and Research Carpal tunnel syndrome Lateral epicondylitis Musculoskeletal Pairwise association Upper extremity |
| title | Pairwise association of upper extremity musculoskeletal conditions: large population investigation from PERSIAN cohort study |
| title_full | Pairwise association of upper extremity musculoskeletal conditions: large population investigation from PERSIAN cohort study |
| title_fullStr | Pairwise association of upper extremity musculoskeletal conditions: large population investigation from PERSIAN cohort study |
| title_full_unstemmed | Pairwise association of upper extremity musculoskeletal conditions: large population investigation from PERSIAN cohort study |
| title_short | Pairwise association of upper extremity musculoskeletal conditions: large population investigation from PERSIAN cohort study |
| title_sort | pairwise association of upper extremity musculoskeletal conditions large population investigation from persian cohort study |
| topic | Carpal tunnel syndrome Lateral epicondylitis Musculoskeletal Pairwise association Upper extremity |
| url | https://doi.org/10.1186/s13018-023-04108-6 |
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