CD1d-independent NK1.1+ Treg cells are IL2-inducible Foxp3+ T cells co-expressing immunosuppressive and cytotoxic molecules

CD1d-independent NK1.1+ Treg cells are IL2-inducible Foxp3+ T cells co-expressing immunosuppressive and cytotoxic molecules

Regulatory T cells (Treg) play pivotal roles in maintaining self-tolerance and preventing immunological diseases such as allergy and autoimmunity through their immunosuppressive properties. Although Treg cells are heterogeneous populations with distinct suppressive functions, expression of natural k...

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Bibliographic Details
Main Authors: Hyun Jung Park, Sung Won Lee, Yun Hoo Park, Tae-Cheol Kim, Luc Van Kaer, Seokmann Hong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
Treg cells
NK1.1
IFNγ
CD1d-independent NKT-like cells
IL2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.951592/full

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