Randomized controlled phase I/II study to investigate immune stimulatory effects by low dose radiotherapy in primarily operable pancreatic cancer

Randomized controlled phase I/II study to investigate immune stimulatory effects by low dose radiotherapy in primarily operable pancreatic cancer

<p>Abstract</p> <p>Background</p> <p>The efficiencies of T cell based immunotherapies are affected by insufficient migration and activation of tumor specific effector T cells in the tumor. Accumulating evidence exists on the ability of ionizing radiation to modify the t...

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Main Authors: Debus Juergen, Buechler Markus W, Tjaden Christine, Koch Moritz, Rochet Nathalie, Reissfelder Christoph, Bonertz Andreas, Roeder Falk FF, Klug Felix, Winnenthal Hubertus, Timke Carmen, Werner Jens, Beckhove Philipp, Weitz Jürgen, Huber Peter E
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Cancer
Subjects:
pancreatic cancer
immune therapy
low dose radiation
T-cells
Online Access:http://www.biomedcentral.com/1471-2407/11/134

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