Inhibitory Effects of Auraptene and Naringin on Astroglial Activation, Tau Hyperphosphorylation, and Suppression of Neurogenesis in the Hippocampus of Streptozotocin-Induced Hyperglycemic Mice

Inhibitory Effects of Auraptene and Naringin on Astroglial Activation, Tau Hyperphosphorylation, and Suppression of Neurogenesis in the Hippocampus of Streptozotocin-Induced Hyperglycemic Mice

Auraptene, a citrus-related compound, exerts anti-inflammatory effects in peripheral tissues, and we demonstrated these effects in the brains of a lipopolysaccharide-injected systemic inflammation animal model and a brain ischemic mouse model. Naringin, another citrus-related compound, has been show...

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Bibliographic Details
Main Authors: Satoshi Okuyama, Tatsumi Nakashima, Kumi Nakamura, Wakana Shinoka, Maho Kotani, Atsushi Sawamoto, Mitsunari Nakajima, Yoshiko Furukawa
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Antioxidants
Subjects:
auraptene
naringin
hyperglycemia
neurogenesis
tau phosphorylation
anti-inflammation
anti-oxidation
Online Access:http://www.mdpi.com/2076-3921/7/8/109

Internet

http://www.mdpi.com/2076-3921/7/8/109

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