Transcriptomics-proteomics Integration reveals alternative polyadenylation driving inflammation-related protein translation in patients with diabetic nephropathy

Transcriptomics-proteomics Integration reveals alternative polyadenylation driving inflammation-related protein translation in patients with diabetic nephropathy

Abstract Background Diabetic nephropathy (DN) is a complex disease involving the upregulation of many inflammation-related proteins. Alternative polyadenylation (APA), a crucial post-transcriptional regulatory mechanism, has been proven to play vital roles in many inflammatory diseases. However, it...

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Bibliographic Details
Main Authors:	Tingting Zhao, Dongdong Zhan, Shuang Qu, Song Jiang, Wenhua Gan, Weisong Qin, Chunxia Zheng, Fang Cheng, Yinghui Lu, Mingwei Liu, Jinsong Shi, Hongwei Liang, Yi Wang, Jun Qin, Ke Zen, Zhihong Liu
Format:	Article
Language:	English
Published:	BMC 2023-02-01
Series:	Journal of Translational Medicine
Subjects:	Diabetic nephropathy Glomeruli Alternative polyadenylation Transcriptomics Proteomics
Online Access:	https://doi.org/10.1186/s12967-023-03934-w

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