IGF2BP2 promotes head and neck squamous carcinoma cell proliferation and growth via the miR-98-5p/PI3K/Akt signaling pathway
IntroductionAs a N6-methyladenosine reader protein, Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a critical player in tumor progression and metastasis. However, its specific function in head and neck squamous carcinoma (HNSCC) has yet to be determined. The present study aimed to...
Main Authors: | Dan Yu, Zhenlong Xiao, Zhefei Zou, Ling Lin, Jing Li, Jian Tan, Wei Chen |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-10-01
|
Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1252999/full |
Similar Items
-
Up-regulation of IGF2BP2 by multiple mechanisms in pancreatic cancer promotes cancer proliferation by activating the PI3K/Akt signaling pathway
by: Xiaodong Xu, et al.
Published: (2019-12-01) -
METTL3/IGF2BP2 Promotes the Malignant Progression of Esophageal Cancer by Activating the PIK3CA/AKT Pathway
by: Xinmeng Guo, et al.
Published: (2025-02-01) -
IGF2BP3 May Contributes to Lung Tumorigenesis by Regulating the Alternative Splicing of PKM
by: Huang Xueqing, et al.
Published: (2020-09-01) -
Identification of Two m6A Readers YTHDF1 and IGF2BP2 as Immune Biomarkers in Head and Neck Squamous Cell Carcinoma
by: Shaojie Li, et al.
Published: (2022-05-01) -
Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation
by: Xiao-Tong Lin, et al.
Published: (2021-11-01)