Isolation and characterization of a metastatic hybrid cell line generated by ER negative and ER positive breast cancer cells in mouse bone marrow.

Isolation and characterization of a metastatic hybrid cell line generated by ER negative and ER positive breast cancer cells in mouse bone marrow.

The origin and the contribution of breast tumor heterogeneity to its progression are not clear. We investigated the effect of a growing orthotopic tumor formed by an aggressive estrogen receptor (ER)-negative breast cancer cell line on the metastatic potential of a less aggressive ER-positive breast...

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Bibliographic Details
Main Authors: Keya De Mukhopadhyay, Abhik Bandyopadhyay, Ting-Tung A Chang, Abdel G Elkahloun, John E Cornell, Junhua Yang, Beth A Goins, I-Tien Yeh, Lu-Zhe Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3106006?pdf=render

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