Spectrum of Mesenchymal–Epithelial Transition Aberrations and Potential Clinical Implications: Insights From Integrative Pancancer Analysis

Spectrum of Mesenchymal–Epithelial Transition Aberrations and Potential Clinical Implications: Insights From Integrative Pancancer Analysis

BackgroundThe receptor tyrosine kinase mesenchymal–epithelial transition factor (MET) is frequently altered in cancers and is a common therapeutic target for cancers with MET variants. However, abnormal MET alterations and their associations with patient outcome across different cancer types have no...

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Bibliographic Details
Main Authors: Juanni Li, Kuan Hu, Lei Zhou, Jinzhou Huang, Shuangshuang Zeng, Zhijie Xu, Yuanliang Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
mesenchymal–epithelial transition factor
gene mutation
gene alteration
outcome
pancancer
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.560615/full

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