Genome‐wide adaptive evolution to underground stresses in subterranean mammals: Hypoxia adaption, immunity promotion, and sensory specialization
Abstract Life underground has provided remarkable examples of adaptive evolution in subterranean mammals; however, genome‐wide adaptive evolution to underground stresses still needs further research. There are approximately 250 species of subterranean mammals across three suborders and six families....
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-07-01
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| Series: | Ecology and Evolution |
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| Online Access: | https://doi.org/10.1002/ece3.6462 |
| _version_ | 1831539585203568640 |
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| author | Mengwan Jiang Luye Shi Xiujuan Li Qianqian Dong Hong Sun Yimeng Du Yifeng Zhang Tian Shao Han Cheng Weihua Chen Zhenlong Wang |
| author_facet | Mengwan Jiang Luye Shi Xiujuan Li Qianqian Dong Hong Sun Yimeng Du Yifeng Zhang Tian Shao Han Cheng Weihua Chen Zhenlong Wang |
| author_sort | Mengwan Jiang |
| collection | DOAJ |
| description | Abstract Life underground has provided remarkable examples of adaptive evolution in subterranean mammals; however, genome‐wide adaptive evolution to underground stresses still needs further research. There are approximately 250 species of subterranean mammals across three suborders and six families. These species not only inhabit hypoxic and dark burrows but also exhibit evolved adaptation to hypoxia, cancer resistance, and specialized sensory systems, making them an excellent model of evolution. The adaptive evolution of subterranean mammals has attracted great attention and needs further study. In the present study, phylogenetic analysis of 5,853 single‐copy orthologous gene families of five subterranean mammals (Nannospalax galili, Heterocephalus glaber, Fukomys damarensis, Condylura cristata, and Chrysochloris asiatica) showed that they formed fou distinct clusters. This result is consistent with the traditional systematics of these species. Furthermore, comparison of the high‐quality genomes of these five subterranean mammalian species led to the identification of the genomic signatures of adaptive evolution. Our results show that the five subterranean mammalian did not share positively selected genes but had similar functional enrichment categories, including hypoxia tolerance, immunity promotion, and sensory specialization, which adapted to the environment of underground stresses. Moreover, variations in soil hardness, climate, and lifestyles have resulted in different molecular mechanisms of adaptation to the hypoxic environment and different degrees of visual degradation. These results provide insights into the genome‐wide adaptive evolution to underground stresses in subterranean mammals, with special focus on the characteristics of hypoxia adaption, immunity promotion, and sensory specialization response to the life underground. |
| first_indexed | 2024-12-16T23:44:09Z |
| format | Article |
| id | doaj.art-48d6b18c09b84633b4fc4c15a57dade0 |
| institution | Directory Open Access Journal |
| issn | 2045-7758 |
| language | English |
| last_indexed | 2024-12-16T23:44:09Z |
| publishDate | 2020-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | Ecology and Evolution |
| spelling | doaj.art-48d6b18c09b84633b4fc4c15a57dade02022-12-21T22:11:32ZengWileyEcology and Evolution2045-77582020-07-0110147377738810.1002/ece3.6462Genome‐wide adaptive evolution to underground stresses in subterranean mammals: Hypoxia adaption, immunity promotion, and sensory specializationMengwan Jiang0Luye Shi1Xiujuan Li2Qianqian Dong3Hong Sun4Yimeng Du5Yifeng Zhang6Tian Shao7Han Cheng8Weihua Chen9Zhenlong Wang10School of Life Sciences Zhengzhou University Zhengzhou ChinaSchool of Life Sciences Zhengzhou University Zhengzhou ChinaSchool of Life Sciences Zhengzhou University Zhengzhou ChinaSchool of Life Sciences Zhengzhou University Zhengzhou ChinaSchool of Life Sciences Zhengzhou University Zhengzhou ChinaSchool of Life Sciences Zhengzhou University Zhengzhou ChinaSchool of Life Sciences Zhengzhou University Zhengzhou ChinaSchool of Life Sciences Zhengzhou University Zhengzhou ChinaSchool of Life Sciences Zhengzhou University Zhengzhou ChinaCollege of Life Science and Technology Huazhong University of Science and Technology Wuhan ChinaSchool of Life Sciences Zhengzhou University Zhengzhou ChinaAbstract Life underground has provided remarkable examples of adaptive evolution in subterranean mammals; however, genome‐wide adaptive evolution to underground stresses still needs further research. There are approximately 250 species of subterranean mammals across three suborders and six families. These species not only inhabit hypoxic and dark burrows but also exhibit evolved adaptation to hypoxia, cancer resistance, and specialized sensory systems, making them an excellent model of evolution. The adaptive evolution of subterranean mammals has attracted great attention and needs further study. In the present study, phylogenetic analysis of 5,853 single‐copy orthologous gene families of five subterranean mammals (Nannospalax galili, Heterocephalus glaber, Fukomys damarensis, Condylura cristata, and Chrysochloris asiatica) showed that they formed fou distinct clusters. This result is consistent with the traditional systematics of these species. Furthermore, comparison of the high‐quality genomes of these five subterranean mammalian species led to the identification of the genomic signatures of adaptive evolution. Our results show that the five subterranean mammalian did not share positively selected genes but had similar functional enrichment categories, including hypoxia tolerance, immunity promotion, and sensory specialization, which adapted to the environment of underground stresses. Moreover, variations in soil hardness, climate, and lifestyles have resulted in different molecular mechanisms of adaptation to the hypoxic environment and different degrees of visual degradation. These results provide insights into the genome‐wide adaptive evolution to underground stresses in subterranean mammals, with special focus on the characteristics of hypoxia adaption, immunity promotion, and sensory specialization response to the life underground.https://doi.org/10.1002/ece3.6462adaptation to hypoxiaadaptive evolutionimmunity promotionsensory specializationsubterranean mammals |
| spellingShingle | Mengwan Jiang Luye Shi Xiujuan Li Qianqian Dong Hong Sun Yimeng Du Yifeng Zhang Tian Shao Han Cheng Weihua Chen Zhenlong Wang Genome‐wide adaptive evolution to underground stresses in subterranean mammals: Hypoxia adaption, immunity promotion, and sensory specialization Ecology and Evolution adaptation to hypoxia adaptive evolution immunity promotion sensory specialization subterranean mammals |
| title | Genome‐wide adaptive evolution to underground stresses in subterranean mammals: Hypoxia adaption, immunity promotion, and sensory specialization |
| title_full | Genome‐wide adaptive evolution to underground stresses in subterranean mammals: Hypoxia adaption, immunity promotion, and sensory specialization |
| title_fullStr | Genome‐wide adaptive evolution to underground stresses in subterranean mammals: Hypoxia adaption, immunity promotion, and sensory specialization |
| title_full_unstemmed | Genome‐wide adaptive evolution to underground stresses in subterranean mammals: Hypoxia adaption, immunity promotion, and sensory specialization |
| title_short | Genome‐wide adaptive evolution to underground stresses in subterranean mammals: Hypoxia adaption, immunity promotion, and sensory specialization |
| title_sort | genome wide adaptive evolution to underground stresses in subterranean mammals hypoxia adaption immunity promotion and sensory specialization |
| topic | adaptation to hypoxia adaptive evolution immunity promotion sensory specialization subterranean mammals |
| url | https://doi.org/10.1002/ece3.6462 |
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