Antibody attributes, Fc receptor expression, gestation and maternal SARS-CoV-2 infection modulate HSV IgG placental transfer

Summary: Antibody-dependent cellular cytotoxicity (ADCC) is associated with protection against neonatal herpes. We hypothesized that placental transfer of ADCC-mediating herpes simplex virus (HSV) immunoglobulin G (IgG) is influenced by antigenic target, function, glycans, gestational age, and mater...

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Bibliographic Details
Main Authors: Aakash Mahant Mahant, Fatima Estrada Trejo, Jennifer T. Aguilan, Simone Sidoli, Sallie R. Permar, Betsy C. Herold
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422301725X