Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study
There is a significant change in the bacterial plaque populations in the oral cavity during and after orthodontic treatment. Numerous studies have demonstrated that 2–96% of patients could increase the risk of white spot lesions. <i>Streptococcus mutans</i> and <i>Lactobacilli</...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-01-01
|
| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/24/2/1401 |
| _version_ | 1797441345310162944 |
|---|---|
| author | Jesús-David Tristán-López Nereyda Niño-Martínez Eleazar-Samuel Kolosovas-Machuca Nuria Patiño-Marín Idania De Alba-Montero Horacio Bach Gabriel-Alejandro Martínez-Castañón |
| author_facet | Jesús-David Tristán-López Nereyda Niño-Martínez Eleazar-Samuel Kolosovas-Machuca Nuria Patiño-Marín Idania De Alba-Montero Horacio Bach Gabriel-Alejandro Martínez-Castañón |
| author_sort | Jesús-David Tristán-López |
| collection | DOAJ |
| description | There is a significant change in the bacterial plaque populations in the oral cavity during and after orthodontic treatment. Numerous studies have demonstrated that 2–96% of patients could increase the risk of white spot lesions. <i>Streptococcus mutans</i> and <i>Lactobacilli</i> ssp. are responsible for these white spot lesions. In this work, silver nanoparticles (AgNPs) with a diameter of 11 nm and dispersed in water were impregnated onto three different commercial orthodontic adhesives at 535 μg/mL. The shear bond strength (SBS) was assessed on 180 human premolars and metallic brackets. The premolars were divided into six groups (three groups for the commercial adhesives and three groups for the adhesives with AgNPs). All the groups were tested for their bactericidal properties, and their MIC, MBC, and agar template diffusion assays were measured. After adding AgNPs, the SBS was not significantly modified for any adhesive (<i>p</i> > 0.05), and the forces measured during the SBS did not exceed the threshold of 6 to 8 MPa for clinical acceptability in all groups. An increase in the bactericidal properties against both <i>S. mutans</i> and <i>L. acidophilus</i> was measured when the adhesives were supplemented with AgNPs. It was concluded that AgNPs can be supplement commercial orthodontic adhesives without modifying their mechanical properties with improved bactericidal activity. |
| first_indexed | 2024-03-09T12:21:41Z |
| format | Article |
| id | doaj.art-48db5ae035f049bcbba51afbc6fbab5e |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-09T12:21:41Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-48db5ae035f049bcbba51afbc6fbab5e2023-11-30T22:39:52ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-01-01242140110.3390/ijms24021401Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro StudyJesús-David Tristán-López0Nereyda Niño-Martínez1Eleazar-Samuel Kolosovas-Machuca2Nuria Patiño-Marín3Idania De Alba-Montero4Horacio Bach5Gabriel-Alejandro Martínez-Castañón6Doctorado Institucional en Ingeniería y Ciencia de Materiales, Universidad Autonoma de San Luis Potosi, Sierra Leona No. 550 Col. Lomas 2da. Sección, C. P., San Luis Potosí 78210, MexicoFacultad de Ciencias, Universidad Autonoma de San Luis Potosi, Av. Parque Chapultepec 1570, Privadas del Pedregal, C. P., San Luis Potosí 78295, MexicoFacultad de Ciencias, Universidad Autonoma de San Luis Potosi, Av. Parque Chapultepec 1570, Privadas del Pedregal, C. P., San Luis Potosí 78295, MexicoFacultad de Estomatología, Universidad Autonoma de San Luis Potosi, Av. Dr. Manuel Nava No. 2, Zona Universitaria, C. P., San Luis Potosí 78290, MexicoFacultad de Ciencias, Universidad Autonoma de San Luis Potosi, Av. Parque Chapultepec 1570, Privadas del Pedregal, C. P., San Luis Potosí 78295, MexicoFaculty of Medicine, Division of Infectious Diseases, University of British Columbia, Vancouver, BC V6H3Z6, CanadaFacultad de Estomatología, Universidad Autonoma de San Luis Potosi, Av. Dr. Manuel Nava No. 2, Zona Universitaria, C. P., San Luis Potosí 78290, MexicoThere is a significant change in the bacterial plaque populations in the oral cavity during and after orthodontic treatment. Numerous studies have demonstrated that 2–96% of patients could increase the risk of white spot lesions. <i>Streptococcus mutans</i> and <i>Lactobacilli</i> ssp. are responsible for these white spot lesions. In this work, silver nanoparticles (AgNPs) with a diameter of 11 nm and dispersed in water were impregnated onto three different commercial orthodontic adhesives at 535 μg/mL. The shear bond strength (SBS) was assessed on 180 human premolars and metallic brackets. The premolars were divided into six groups (three groups for the commercial adhesives and three groups for the adhesives with AgNPs). All the groups were tested for their bactericidal properties, and their MIC, MBC, and agar template diffusion assays were measured. After adding AgNPs, the SBS was not significantly modified for any adhesive (<i>p</i> > 0.05), and the forces measured during the SBS did not exceed the threshold of 6 to 8 MPa for clinical acceptability in all groups. An increase in the bactericidal properties against both <i>S. mutans</i> and <i>L. acidophilus</i> was measured when the adhesives were supplemented with AgNPs. It was concluded that AgNPs can be supplement commercial orthodontic adhesives without modifying their mechanical properties with improved bactericidal activity.https://www.mdpi.com/1422-0067/24/2/1401silver nanoparticlesorthodontic adhesivesadhesivesshear bond strengthbactericidal activity |
| spellingShingle | Jesús-David Tristán-López Nereyda Niño-Martínez Eleazar-Samuel Kolosovas-Machuca Nuria Patiño-Marín Idania De Alba-Montero Horacio Bach Gabriel-Alejandro Martínez-Castañón Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study International Journal of Molecular Sciences silver nanoparticles orthodontic adhesives adhesives shear bond strength bactericidal activity |
| title | Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study |
| title_full | Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study |
| title_fullStr | Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study |
| title_full_unstemmed | Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study |
| title_short | Application of Silver Nanoparticles to Improve the Antibacterial Activity of Orthodontic Adhesives: An In Vitro Study |
| title_sort | application of silver nanoparticles to improve the antibacterial activity of orthodontic adhesives an in vitro study |
| topic | silver nanoparticles orthodontic adhesives adhesives shear bond strength bactericidal activity |
| url | https://www.mdpi.com/1422-0067/24/2/1401 |
| work_keys_str_mv | AT jesusdavidtristanlopez applicationofsilvernanoparticlestoimprovetheantibacterialactivityoforthodonticadhesivesaninvitrostudy AT nereydaninomartinez applicationofsilvernanoparticlestoimprovetheantibacterialactivityoforthodonticadhesivesaninvitrostudy AT eleazarsamuelkolosovasmachuca applicationofsilvernanoparticlestoimprovetheantibacterialactivityoforthodonticadhesivesaninvitrostudy AT nuriapatinomarin applicationofsilvernanoparticlestoimprovetheantibacterialactivityoforthodonticadhesivesaninvitrostudy AT idaniadealbamontero applicationofsilvernanoparticlestoimprovetheantibacterialactivityoforthodonticadhesivesaninvitrostudy AT horaciobach applicationofsilvernanoparticlestoimprovetheantibacterialactivityoforthodonticadhesivesaninvitrostudy AT gabrielalejandromartinezcastanon applicationofsilvernanoparticlestoimprovetheantibacterialactivityoforthodonticadhesivesaninvitrostudy |