Attention Deficit Hyperactivity Disorder and Bipolar Disorder: Diagnosis, Treatments, and Clinical Considerations: A Narrative Review

Attention-deficit Hyperactivity Disorder is one of the most common childhood mental health disorders, affecting about 5.6% of the population worldwide. Several studies have specifically shown a high prevalence of comorbid mood disorders, such as depression and bipolar disorder (BD), in those diagnos...

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Main Authors: Amber N. Edinoff, Tucker L. Apgar, Jasmine J. Rogers, Joshua D. Harper, Elyse M. Cornett, Adam M. Kaye, Alan D. Kaye
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Psychiatry International
Subjects:
Online Access:https://www.mdpi.com/2673-5318/3/1/2
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author Amber N. Edinoff
Tucker L. Apgar
Jasmine J. Rogers
Joshua D. Harper
Elyse M. Cornett
Adam M. Kaye
Alan D. Kaye
author_facet Amber N. Edinoff
Tucker L. Apgar
Jasmine J. Rogers
Joshua D. Harper
Elyse M. Cornett
Adam M. Kaye
Alan D. Kaye
author_sort Amber N. Edinoff
collection DOAJ
description Attention-deficit Hyperactivity Disorder is one of the most common childhood mental health disorders, affecting about 5.6% of the population worldwide. Several studies have specifically shown a high prevalence of comorbid mood disorders, such as depression and bipolar disorder (BD), in those diagnosed with ADHD. Several common symptoms of ADHD are also found in BD, which are characterized by alternating periods of euthymia and mood disturbances. The inattention and impulsivity of ADHD can be seen in manic and hypomanic episodes of BD. Over the past decade, there has been an increased interest in research between the correlation of ADHD and pediatric bipolar disorder (PBD) in children. Some experts hypothesize that more children are comorbidly diagnosed with ADHD and PBD because of how many clinicians treat children with ADHD. Other factors, which may affect the dual diagnoses of ADHD and PBD, are overlapping diagnostic criteria for the two disorders, the inevitable biases seen when one disorder is diagnosed without the other, and related risk factors leading to prodromal relationships. By examining clinical trials, a better understanding of whether ADHD and PBD have a stepwise progression or if other factors influence these comorbidities, such as blurred lines of diagnostic criteria. Those with ADHD are also at an increased risk of impairment at work and in social settings. This manuscript explores both progression of this disease and its clinical connections to other disorders.
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spelling doaj.art-48dc5c7bd4e74e31839b465ba2164dd12023-11-30T22:08:18ZengMDPI AGPsychiatry International2673-53182021-12-0131172810.3390/psychiatryint3010002Attention Deficit Hyperactivity Disorder and Bipolar Disorder: Diagnosis, Treatments, and Clinical Considerations: A Narrative ReviewAmber N. Edinoff0Tucker L. Apgar1Jasmine J. Rogers2Joshua D. Harper3Elyse M. Cornett4Adam M. Kaye5Alan D. Kaye6Department of Psychiatry and Behavioral Medicine, Louisiana State University Health Science Center Shreveport, Shreveport, LA 71103, USADepartment of Chemical Biology and Biochemistry, Vanderbilt University, Nashville, TN 37235, USASchool of Medicine, Louisiana State University Health Shreveport, Shreveport, LA 71103, USASchool of Medicine, Louisiana State University Health Shreveport, Shreveport, LA 71103, USADepartment of Anesthesiology, Louisiana State University Shreveport, Shreveport, LA 71103, USADepartment of Pharmacy Practice, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, CA 95211, USADepartment of Anesthesiology, Louisiana State University Shreveport, Shreveport, LA 71103, USAAttention-deficit Hyperactivity Disorder is one of the most common childhood mental health disorders, affecting about 5.6% of the population worldwide. Several studies have specifically shown a high prevalence of comorbid mood disorders, such as depression and bipolar disorder (BD), in those diagnosed with ADHD. Several common symptoms of ADHD are also found in BD, which are characterized by alternating periods of euthymia and mood disturbances. The inattention and impulsivity of ADHD can be seen in manic and hypomanic episodes of BD. Over the past decade, there has been an increased interest in research between the correlation of ADHD and pediatric bipolar disorder (PBD) in children. Some experts hypothesize that more children are comorbidly diagnosed with ADHD and PBD because of how many clinicians treat children with ADHD. Other factors, which may affect the dual diagnoses of ADHD and PBD, are overlapping diagnostic criteria for the two disorders, the inevitable biases seen when one disorder is diagnosed without the other, and related risk factors leading to prodromal relationships. By examining clinical trials, a better understanding of whether ADHD and PBD have a stepwise progression or if other factors influence these comorbidities, such as blurred lines of diagnostic criteria. Those with ADHD are also at an increased risk of impairment at work and in social settings. This manuscript explores both progression of this disease and its clinical connections to other disorders.https://www.mdpi.com/2673-5318/3/1/2ADHDbipolar disorderpediatricsstimulantscomorbidity
spellingShingle Amber N. Edinoff
Tucker L. Apgar
Jasmine J. Rogers
Joshua D. Harper
Elyse M. Cornett
Adam M. Kaye
Alan D. Kaye
Attention Deficit Hyperactivity Disorder and Bipolar Disorder: Diagnosis, Treatments, and Clinical Considerations: A Narrative Review
Psychiatry International
ADHD
bipolar disorder
pediatrics
stimulants
comorbidity
title Attention Deficit Hyperactivity Disorder and Bipolar Disorder: Diagnosis, Treatments, and Clinical Considerations: A Narrative Review
title_full Attention Deficit Hyperactivity Disorder and Bipolar Disorder: Diagnosis, Treatments, and Clinical Considerations: A Narrative Review
title_fullStr Attention Deficit Hyperactivity Disorder and Bipolar Disorder: Diagnosis, Treatments, and Clinical Considerations: A Narrative Review
title_full_unstemmed Attention Deficit Hyperactivity Disorder and Bipolar Disorder: Diagnosis, Treatments, and Clinical Considerations: A Narrative Review
title_short Attention Deficit Hyperactivity Disorder and Bipolar Disorder: Diagnosis, Treatments, and Clinical Considerations: A Narrative Review
title_sort attention deficit hyperactivity disorder and bipolar disorder diagnosis treatments and clinical considerations a narrative review
topic ADHD
bipolar disorder
pediatrics
stimulants
comorbidity
url https://www.mdpi.com/2673-5318/3/1/2
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