Skin photoageing: mechanisms of development and particular features of clinical manifestations

The article discloses current concepts of mechanisms of development of skin photoageing caused by UV irradiation (UVA and UVB). Chronic exposure of skin to UV irradiation results in damage of genome DNA, development of DNA mutations, damage of proteins, membrane lipids, collagen and yellow fibers, d...

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Main Authors: A. A. Kubanov, M. B. Zhilova, A. A. Kubanova
Format: Article
Language:English
Published: State Scientific Center of Dermatovenereology and Cosmetology 2017-08-01
Series:Vestnik Dermatologii i Venerologii
Subjects:
Online Access:https://www.vestnikdv.ru/jour/article/view/64
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author A. A. Kubanov
M. B. Zhilova
A. A. Kubanova
author_facet A. A. Kubanov
M. B. Zhilova
A. A. Kubanova
author_sort A. A. Kubanov
collection DOAJ
description The article discloses current concepts of mechanisms of development of skin photoageing caused by UV irradiation (UVA and UVB). Chronic exposure of skin to UV irradiation results in damage of genome DNA, development of DNA mutations, damage of proteins, membrane lipids, collagen and yellow fibers, degradation of the intercellular substance of the skin, development of a chronic inflammation, immunosuppression, melanogenesis disorders and increased angiogenesis. The authors described major clinical manifestations of skin photoageing and their histological characteristics.
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spelling doaj.art-48dc61501b4940f3997ef4b8ffa58a012023-09-02T19:32:59ZengState Scientific Center of Dermatovenereology and CosmetologyVestnik Dermatologii i Venerologii0042-46092313-62942017-08-0105535910.25208/0042-4609-2014-0-5-53-5963Skin photoageing: mechanisms of development and particular features of clinical manifestationsA. A. Kubanov0M. B. Zhilova1A. A. Kubanova2State Research Center of Dermatovenereology and Cosmetology, Ministry of Healthcare of the Russian FederationState Research Center of Dermatovenereology and Cosmetology, Ministry of Healthcare of the Russian FederationState Research Center of Dermatovenereology and Cosmetology, Ministry of Healthcare of the Russian FederationThe article discloses current concepts of mechanisms of development of skin photoageing caused by UV irradiation (UVA and UVB). Chronic exposure of skin to UV irradiation results in damage of genome DNA, development of DNA mutations, damage of proteins, membrane lipids, collagen and yellow fibers, degradation of the intercellular substance of the skin, development of a chronic inflammation, immunosuppression, melanogenesis disorders and increased angiogenesis. The authors described major clinical manifestations of skin photoageing and their histological characteristics.https://www.vestnikdv.ru/jour/article/view/64фотостарениемеханизмыультрафиолетовое излучениеуфауфбphotoageingmechanismsuv irradiationuvauvb
spellingShingle A. A. Kubanov
M. B. Zhilova
A. A. Kubanova
Skin photoageing: mechanisms of development and particular features of clinical manifestations
Vestnik Dermatologii i Venerologii
фотостарение
механизмы
ультрафиолетовое излучение
уфа
уфб
photoageing
mechanisms
uv irradiation
uva
uvb
title Skin photoageing: mechanisms of development and particular features of clinical manifestations
title_full Skin photoageing: mechanisms of development and particular features of clinical manifestations
title_fullStr Skin photoageing: mechanisms of development and particular features of clinical manifestations
title_full_unstemmed Skin photoageing: mechanisms of development and particular features of clinical manifestations
title_short Skin photoageing: mechanisms of development and particular features of clinical manifestations
title_sort skin photoageing mechanisms of development and particular features of clinical manifestations
topic фотостарение
механизмы
ультрафиолетовое излучение
уфа
уфб
photoageing
mechanisms
uv irradiation
uva
uvb
url https://www.vestnikdv.ru/jour/article/view/64
work_keys_str_mv AT aakubanov skinphotoageingmechanismsofdevelopmentandparticularfeaturesofclinicalmanifestations
AT mbzhilova skinphotoageingmechanismsofdevelopmentandparticularfeaturesofclinicalmanifestations
AT aakubanova skinphotoageingmechanismsofdevelopmentandparticularfeaturesofclinicalmanifestations