Road traffic noise and incident myocardial infarction: a prospective cohort study.
<h4>Background</h4>Both road traffic noise and ambient air pollution have been associated with risk for ischemic heart disease, but only few inconsistent studies include both exposures.<h4>Methods</h4>In a population-based cohort of 57 053 people aged 50 to 64 years at enrolm...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22745727/pdf/?tool=EBI |
| _version_ | 1818400407712432128 |
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| author | Mette Sørensen Zorana J Andersen Rikke B Nordsborg Steen S Jensen Kenneth G Lillelund Rob Beelen Erik B Schmidt Anne Tjønneland Kim Overvad Ole Raaschou-Nielsen |
| author_facet | Mette Sørensen Zorana J Andersen Rikke B Nordsborg Steen S Jensen Kenneth G Lillelund Rob Beelen Erik B Schmidt Anne Tjønneland Kim Overvad Ole Raaschou-Nielsen |
| author_sort | Mette Sørensen |
| collection | DOAJ |
| description | <h4>Background</h4>Both road traffic noise and ambient air pollution have been associated with risk for ischemic heart disease, but only few inconsistent studies include both exposures.<h4>Methods</h4>In a population-based cohort of 57 053 people aged 50 to 64 years at enrolment in 1993-1997, we identified 1600 cases of first-ever MI between enrolment and 2006. The mean follow-up time was 9.8 years. Exposure to road traffic noise and air pollution from 1988 to 2006 was estimated for all cohort members from residential address history. Associations between exposure to road traffic noise and incident MI were analysed in a Cox regression model with adjustment for air pollution (NO(x)) and other potential confounders: age, sex, education, lifestyle confounders, railway and airport noise.<h4>Results</h4>We found that residential exposure to road traffic noise (L(den)) was significantly associated with MI, with an incidence rate ratio IRR of 1.12 per 10 dB for both of the two exposure windows: yearly exposure at the time of diagnosis (95% confidence interval (CI): 1.02-1.22) and 5-years time-weighted mean (95% CI: 1.02-1.23) preceding the diagnosis. Visualizing of the results using restricted cubic splines showed a linear dose-response relationship.<h4>Conclusions</h4>Exposure to long-term residential road traffic noise was associated with a higher risk for MI, in a dose-dependent manner. |
| first_indexed | 2024-12-14T07:36:05Z |
| format | Article |
| id | doaj.art-48dd28ebd5b745f2add55adf64134a5b |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-14T07:36:05Z |
| publishDate | 2012-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-48dd28ebd5b745f2add55adf64134a5b2022-12-21T23:11:11ZengPublic Library of Science (PLoS)PLoS ONE1932-62032012-01-0176e3928310.1371/journal.pone.0039283Road traffic noise and incident myocardial infarction: a prospective cohort study.Mette SørensenZorana J AndersenRikke B NordsborgSteen S JensenKenneth G LillelundRob BeelenErik B SchmidtAnne TjønnelandKim OvervadOle Raaschou-Nielsen<h4>Background</h4>Both road traffic noise and ambient air pollution have been associated with risk for ischemic heart disease, but only few inconsistent studies include both exposures.<h4>Methods</h4>In a population-based cohort of 57 053 people aged 50 to 64 years at enrolment in 1993-1997, we identified 1600 cases of first-ever MI between enrolment and 2006. The mean follow-up time was 9.8 years. Exposure to road traffic noise and air pollution from 1988 to 2006 was estimated for all cohort members from residential address history. Associations between exposure to road traffic noise and incident MI were analysed in a Cox regression model with adjustment for air pollution (NO(x)) and other potential confounders: age, sex, education, lifestyle confounders, railway and airport noise.<h4>Results</h4>We found that residential exposure to road traffic noise (L(den)) was significantly associated with MI, with an incidence rate ratio IRR of 1.12 per 10 dB for both of the two exposure windows: yearly exposure at the time of diagnosis (95% confidence interval (CI): 1.02-1.22) and 5-years time-weighted mean (95% CI: 1.02-1.23) preceding the diagnosis. Visualizing of the results using restricted cubic splines showed a linear dose-response relationship.<h4>Conclusions</h4>Exposure to long-term residential road traffic noise was associated with a higher risk for MI, in a dose-dependent manner.https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22745727/pdf/?tool=EBI |
| spellingShingle | Mette Sørensen Zorana J Andersen Rikke B Nordsborg Steen S Jensen Kenneth G Lillelund Rob Beelen Erik B Schmidt Anne Tjønneland Kim Overvad Ole Raaschou-Nielsen Road traffic noise and incident myocardial infarction: a prospective cohort study. PLoS ONE |
| title | Road traffic noise and incident myocardial infarction: a prospective cohort study. |
| title_full | Road traffic noise and incident myocardial infarction: a prospective cohort study. |
| title_fullStr | Road traffic noise and incident myocardial infarction: a prospective cohort study. |
| title_full_unstemmed | Road traffic noise and incident myocardial infarction: a prospective cohort study. |
| title_short | Road traffic noise and incident myocardial infarction: a prospective cohort study. |
| title_sort | road traffic noise and incident myocardial infarction a prospective cohort study |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22745727/pdf/?tool=EBI |
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