Histologic and radiological observations of a human immature premolar with pulp necrosis treated with regenerative endodontic procedure – A case report of a four-year follow-up
Background: Reports are found on long-term radiographic follow-up of teeth treated with regenerative endodontic techniques, but scarce literature is observed regarding the tissue formed in the root canal. A four-year radiographic follow-up with histologic findings in an immature mandibular premolar...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-11-01
|
| Series: | Saudi Dental Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1013905223001530 |
| _version_ | 1797643592032845824 |
|---|---|
| author | Kanwardeep Kaur Eby Varghese Uma Eswara Joanne Goh Pei En |
| author_facet | Kanwardeep Kaur Eby Varghese Uma Eswara Joanne Goh Pei En |
| author_sort | Kanwardeep Kaur |
| collection | DOAJ |
| description | Background: Reports are found on long-term radiographic follow-up of teeth treated with regenerative endodontic techniques, but scarce literature is observed regarding the tissue formed in the root canal. A four-year radiographic follow-up with histologic findings in an immature mandibular premolar with dens evaginatus that underwent a regenerative endodontic procedure (REP) is presented here. After four years following REP, the tooth was extracted for orthodontic purposes thereby presenting an opportunity to report the histologic findings. Summary: The radiographic changes included a slight root lengthening and thickening and apex closure. Histologic evaluation revealed a fibrous connective tissue with an inflammatory infiltrate in the canal space. In the apical region, cementum-like irregular mineralization developed toward the center, giving the appearance of a closed apex. Root thickening, increase in length, and radiographic closure of the apex occurred due to cemental hyperplasia. Conclusion: After 4 years following REP in an immature mandibular premolar with apical periodontitis, granulation tissue had formed in the root canal, indicating repair and not regeneration. |
| first_indexed | 2024-03-11T14:17:07Z |
| format | Article |
| id | doaj.art-48e15b62c1204ccc949a076a6d9f7bb3 |
| institution | Directory Open Access Journal |
| issn | 1013-9052 |
| language | English |
| last_indexed | 2024-03-11T14:17:07Z |
| publishDate | 2023-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Saudi Dental Journal |
| spelling | doaj.art-48e15b62c1204ccc949a076a6d9f7bb32023-11-01T04:46:20ZengElsevierSaudi Dental Journal1013-90522023-11-01357869875Histologic and radiological observations of a human immature premolar with pulp necrosis treated with regenerative endodontic procedure – A case report of a four-year follow-upKanwardeep Kaur0Eby Varghese1Uma Eswara2Joanne Goh Pei En3Faculty of Dentistry, Manipal University College Malaysia, Jalan Batu Hampar, Bukit Baru, Melaka 75150, MalaysiaDepartment of Pediatric Dentistry, Faculty of Dentistry, Manipal University College Malaysia, Jalan Batu Hampar, Bukit Baru, Melaka 75150, Malaysia; Corresponding author.Department of Pediatric Dentistry, Faculty of Dentistry, Manipal University College Malaysia, Jalan Batu Hampar, Bukit Baru, Melaka 75150, MalaysiaDepartment of Oral and Maxillofacial Clinical Science, Faculty of Dentistry, University of Malaya, MalaysiaBackground: Reports are found on long-term radiographic follow-up of teeth treated with regenerative endodontic techniques, but scarce literature is observed regarding the tissue formed in the root canal. A four-year radiographic follow-up with histologic findings in an immature mandibular premolar with dens evaginatus that underwent a regenerative endodontic procedure (REP) is presented here. After four years following REP, the tooth was extracted for orthodontic purposes thereby presenting an opportunity to report the histologic findings. Summary: The radiographic changes included a slight root lengthening and thickening and apex closure. Histologic evaluation revealed a fibrous connective tissue with an inflammatory infiltrate in the canal space. In the apical region, cementum-like irregular mineralization developed toward the center, giving the appearance of a closed apex. Root thickening, increase in length, and radiographic closure of the apex occurred due to cemental hyperplasia. Conclusion: After 4 years following REP in an immature mandibular premolar with apical periodontitis, granulation tissue had formed in the root canal, indicating repair and not regeneration.http://www.sciencedirect.com/science/article/pii/S1013905223001530Dens evaginatusRegenerative endodontic procedureImmature toothOpen apex |
| spellingShingle | Kanwardeep Kaur Eby Varghese Uma Eswara Joanne Goh Pei En Histologic and radiological observations of a human immature premolar with pulp necrosis treated with regenerative endodontic procedure – A case report of a four-year follow-up Saudi Dental Journal Dens evaginatus Regenerative endodontic procedure Immature tooth Open apex |
| title | Histologic and radiological observations of a human immature premolar with pulp necrosis treated with regenerative endodontic procedure – A case report of a four-year follow-up |
| title_full | Histologic and radiological observations of a human immature premolar with pulp necrosis treated with regenerative endodontic procedure – A case report of a four-year follow-up |
| title_fullStr | Histologic and radiological observations of a human immature premolar with pulp necrosis treated with regenerative endodontic procedure – A case report of a four-year follow-up |
| title_full_unstemmed | Histologic and radiological observations of a human immature premolar with pulp necrosis treated with regenerative endodontic procedure – A case report of a four-year follow-up |
| title_short | Histologic and radiological observations of a human immature premolar with pulp necrosis treated with regenerative endodontic procedure – A case report of a four-year follow-up |
| title_sort | histologic and radiological observations of a human immature premolar with pulp necrosis treated with regenerative endodontic procedure a case report of a four year follow up |
| topic | Dens evaginatus Regenerative endodontic procedure Immature tooth Open apex |
| url | http://www.sciencedirect.com/science/article/pii/S1013905223001530 |
| work_keys_str_mv | AT kanwardeepkaur histologicandradiologicalobservationsofahumanimmaturepremolarwithpulpnecrosistreatedwithregenerativeendodonticprocedureacasereportofafouryearfollowup AT ebyvarghese histologicandradiologicalobservationsofahumanimmaturepremolarwithpulpnecrosistreatedwithregenerativeendodonticprocedureacasereportofafouryearfollowup AT umaeswara histologicandradiologicalobservationsofahumanimmaturepremolarwithpulpnecrosistreatedwithregenerativeendodonticprocedureacasereportofafouryearfollowup AT joannegohpeien histologicandradiologicalobservationsofahumanimmaturepremolarwithpulpnecrosistreatedwithregenerativeendodonticprocedureacasereportofafouryearfollowup |