Effect of vitamin D3 on the cytokine synthesizing activity of cells of gingival fluid
Purpose: to study the effect of vitamin D3 on cytokine activity of macrophages and monocytes of gingival fluid. Material and methods. The examination and treatment of 42 patients with chronic generalized periodontitis at the age of 45-50 years were conducted. Gingival fluid was obtained from the per...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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Saratov State Medical University
2016-09-01
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| Series: | Саратовский научно-медицинский журнал |
| Subjects: | |
| Online Access: | http://www.ssmj.ru/system/files/2016_03_403-407.pdf |
| _version_ | 1818585264919937024 |
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| author | Ostrovskaya L.Yu. Zakharova N.B. Mogila А.Р. Katkhanova L.S. Akulova E.V. Lysov A.V. |
| author_facet | Ostrovskaya L.Yu. Zakharova N.B. Mogila А.Р. Katkhanova L.S. Akulova E.V. Lysov A.V. |
| author_sort | Ostrovskaya L.Yu. |
| collection | DOAJ |
| description | Purpose: to study the effect of vitamin D3 on cytokine activity of macrophages and monocytes of gingival fluid. Material and methods. The examination and treatment of 42 patients with chronic generalized periodontitis at the age of 45-50 years were conducted. Gingival fluid was obtained from the periodontal pockets of patients. Material processed statistically. Results. Colecalciferol efficacy in inflammation and processes of destruction of periodontal tissue was twice higher than using traditional therapy. Resistance anti-inflammatory effect of the drug was maintained for 6 months, which had been confirmed by clinical and laboratory investigations. Conclusion. The use of applications of vitamin D in the treatment of periodontitis may achieve compensatory restoration of immune protection of the oral cavity. |
| first_indexed | 2024-12-16T08:34:19Z |
| format | Article |
| id | doaj.art-48e42ebbf4b74b92b0e0e99f80a36fab |
| institution | Directory Open Access Journal |
| issn | 2076-2518 |
| language | Russian |
| last_indexed | 2024-12-16T08:34:19Z |
| publishDate | 2016-09-01 |
| publisher | Saratov State Medical University |
| record_format | Article |
| series | Саратовский научно-медицинский журнал |
| spelling | doaj.art-48e42ebbf4b74b92b0e0e99f80a36fab2022-12-21T22:37:48ZrusSaratov State Medical UniversityСаратовский научно-медицинский журнал2076-25182016-09-011234034074422Effect of vitamin D3 on the cytokine synthesizing activity of cells of gingival fluidOstrovskaya L.Yu.0Zakharova N.B.1Mogila А.Р.2Katkhanova L.S.3Akulova E.V.4Lysov A.V.5Saratov State Medical UniversitySaratov State Medical UniversitySaratov State Medical UniversitySaratov State Medical UniversitySaratov State Medical UniversitySaratov State Medical UniversityPurpose: to study the effect of vitamin D3 on cytokine activity of macrophages and monocytes of gingival fluid. Material and methods. The examination and treatment of 42 patients with chronic generalized periodontitis at the age of 45-50 years were conducted. Gingival fluid was obtained from the periodontal pockets of patients. Material processed statistically. Results. Colecalciferol efficacy in inflammation and processes of destruction of periodontal tissue was twice higher than using traditional therapy. Resistance anti-inflammatory effect of the drug was maintained for 6 months, which had been confirmed by clinical and laboratory investigations. Conclusion. The use of applications of vitamin D in the treatment of periodontitis may achieve compensatory restoration of immune protection of the oral cavity.http://www.ssmj.ru/system/files/2016_03_403-407.pdfcytokinesmenopauseparodontitisvitamin D3 |
| spellingShingle | Ostrovskaya L.Yu. Zakharova N.B. Mogila А.Р. Katkhanova L.S. Akulova E.V. Lysov A.V. Effect of vitamin D3 on the cytokine synthesizing activity of cells of gingival fluid Саратовский научно-медицинский журнал cytokines menopause parodontitis vitamin D3 |
| title | Effect of vitamin D3 on the cytokine synthesizing activity of cells of gingival fluid |
| title_full | Effect of vitamin D3 on the cytokine synthesizing activity of cells of gingival fluid |
| title_fullStr | Effect of vitamin D3 on the cytokine synthesizing activity of cells of gingival fluid |
| title_full_unstemmed | Effect of vitamin D3 on the cytokine synthesizing activity of cells of gingival fluid |
| title_short | Effect of vitamin D3 on the cytokine synthesizing activity of cells of gingival fluid |
| title_sort | effect of vitamin d3 on the cytokine synthesizing activity of cells of gingival fluid |
| topic | cytokines menopause parodontitis vitamin D3 |
| url | http://www.ssmj.ru/system/files/2016_03_403-407.pdf |
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