Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results
Introduction: MIE is becoming a preferred approach for cancer of esophagus and GE junction, but its benefits have yet to be confirmed in randomized controlled trials. We performed a retrospective comparison between these two approaches for complications and survival results. Methods: Patients prima...
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| Format: | Article |
| Language: | English |
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Society of Surgeons of Nepal
2016-07-01
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| Series: | Journal of Society of Surgeons of Nepal |
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| Online Access: | https://www.nepjol.info/index.php/JSSN/article/view/15267 |
| _version_ | 1819237274402947072 |
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| author | Binay Thakur Di Yonghui Mukti Devkota Paribartan Baral Yogesh Regmi Rajendra Malli Upsana Tiwari |
| author_facet | Binay Thakur Di Yonghui Mukti Devkota Paribartan Baral Yogesh Regmi Rajendra Malli Upsana Tiwari |
| author_sort | Binay Thakur |
| collection | DOAJ |
| description | Introduction: MIE is becoming a preferred approach for cancer of esophagus and GE junction, but its benefits have yet to be confirmed in randomized controlled trials. We performed a retrospective comparison between these two approaches for complications and survival results.
Methods: Patients primarily going for surgery or after neoadjuvant chemo/ chemoradiation were reviewed. MIE varied from totally thoracoscopic and laparoscopic to a hybrid approach. Both MIE and Open approaches were a three, two or one incision procedures.
Results: MIE and open surgery were done in 128 and 293 patients, respectively. The mean basic parameters (referred as MIE/ Open) – age (59/ 57 years), duration of dysphagia (4/ 4 months), weight loss (8/ 9 kg), postoperative stay (13/ 14 days), hospital mortality (3/ 17), anastomotic leak (17/ 32), hoarseness of voice (8/ 16), number of harvested nodes (21/ 22), and R0 resection (122/ 263) did not differ significantly (p = ns). Mean operative time (265/ 240 mins) and intraoperative blood loss (325/ 436 ml) differed significantly (p < 0.05). Postoperative pneumonia was significantly less in MIE group (p<0.001). Median and 5-year overall survival was 33 months and 21% in MIE group; and 27 months and 20% in open group (p = 0.2)
Conclusion: MIE and Open surgery did not differ in major postoperative complications except postoperative pneumonia, which was less in MIE. Both the procedures were similar in achieving R0 resection, median and 5-year overall survival. |
| first_indexed | 2024-12-23T13:17:44Z |
| format | Article |
| id | doaj.art-48e536ea978d459ebdecb43314016771 |
| institution | Directory Open Access Journal |
| issn | 1815-3984 2392-4772 |
| language | English |
| last_indexed | 2024-12-23T13:17:44Z |
| publishDate | 2016-07-01 |
| publisher | Society of Surgeons of Nepal |
| record_format | Article |
| series | Journal of Society of Surgeons of Nepal |
| spelling | doaj.art-48e536ea978d459ebdecb433140167712022-12-21T17:45:32ZengSociety of Surgeons of NepalJournal of Society of Surgeons of Nepal1815-39842392-47722016-07-0118310.3126/jssn.v18i3.15267Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term resultsBinay ThakurDi YonghuiMukti DevkotaParibartan BaralYogesh RegmiRajendra MalliUpsana TiwariIntroduction: MIE is becoming a preferred approach for cancer of esophagus and GE junction, but its benefits have yet to be confirmed in randomized controlled trials. We performed a retrospective comparison between these two approaches for complications and survival results. Methods: Patients primarily going for surgery or after neoadjuvant chemo/ chemoradiation were reviewed. MIE varied from totally thoracoscopic and laparoscopic to a hybrid approach. Both MIE and Open approaches were a three, two or one incision procedures. Results: MIE and open surgery were done in 128 and 293 patients, respectively. The mean basic parameters (referred as MIE/ Open) – age (59/ 57 years), duration of dysphagia (4/ 4 months), weight loss (8/ 9 kg), postoperative stay (13/ 14 days), hospital mortality (3/ 17), anastomotic leak (17/ 32), hoarseness of voice (8/ 16), number of harvested nodes (21/ 22), and R0 resection (122/ 263) did not differ significantly (p = ns). Mean operative time (265/ 240 mins) and intraoperative blood loss (325/ 436 ml) differed significantly (p < 0.05). Postoperative pneumonia was significantly less in MIE group (p<0.001). Median and 5-year overall survival was 33 months and 21% in MIE group; and 27 months and 20% in open group (p = 0.2) Conclusion: MIE and Open surgery did not differ in major postoperative complications except postoperative pneumonia, which was less in MIE. Both the procedures were similar in achieving R0 resection, median and 5-year overall survival.https://www.nepjol.info/index.php/JSSN/article/view/15267Esophageal cancerMckeon’s esophagectomyVATS |
| spellingShingle | Binay Thakur Di Yonghui Mukti Devkota Paribartan Baral Yogesh Regmi Rajendra Malli Upsana Tiwari Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results Journal of Society of Surgeons of Nepal Esophageal cancer Mckeon’s esophagectomy VATS |
| title | Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results |
| title_full | Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results |
| title_fullStr | Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results |
| title_full_unstemmed | Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results |
| title_short | Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results |
| title_sort | minimally invasive mie vs open surgery for cancer of esophagus and ge junction long term results |
| topic | Esophageal cancer Mckeon’s esophagectomy VATS |
| url | https://www.nepjol.info/index.php/JSSN/article/view/15267 |
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