Molecular Mechanisms of Gonadotropin-Inhibitory Hormone (GnIH) Actions in Target Cells and Regulation of GnIH Expression

Molecular Mechanisms of Gonadotropin-Inhibitory Hormone (GnIH) Actions in Target Cells and Regulation of GnIH Expression

Since gonadotropin-inhibitory hormone (GnIH) was discovered in 2000 as the first hypothalamic neuropeptide that actively inhibits gonadotropin release, researches conducted for the last 18 years have demonstrated that GnIH acts as a pronounced negative regulator of reproduction. Inhibitory effect of...

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Bibliographic Details
Main Authors:	You Lee Son, Takayoshi Ubuka, Kazuyoshi Tsutsui
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-02-01
Series:	Frontiers in Endocrinology
Subjects:	gonadotropin-inhibitory hormone/RFamide-related peptides (GnIH/RFRPs) GnIH receptor (GnIH-R) gonadotropin-releasing hormone (GnRH) kisspeptin vasoactive intestinal polypeptide (VIP) gonadotropes
Online Access:	https://www.frontiersin.org/article/10.3389/fendo.2019.00110/full

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