Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis

Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis

The persistence of macrophage-derived foam cells in the artery wall fuels atherosclerosis development. However, the mechanism of foam cell formation regulation remains elusive. We are committed to determining the role that CD147 might play in macrophage foam cell formation during atherosclerosis. In...

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Bibliographic Details
Main Authors: Jian-Jun Lv, Hao Wang, Hong-Yong Cui, Ze-Kun Liu, Ren-Yu Zhang, Meng Lu, Can Li, Yu-Le Yong, Man Liu, Hai Zhang, Tian-Jiao Zhang, Kun Zhang, Gang Li, Gang Nan, Cong Zhang, Shuang-Ping Guo, Ling Wang, Zhi-Nan Chen, Huijie Bian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
atherosclerosis
foam cell formation
macrophage
CD147
CD36
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.609090/full

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