Cholesterol as an Endogenous Ligand of ERRα Promotes ERRα-Mediated Cellular Proliferation and Metabolic Target Gene Expression in Breast Cancer Cells

Breast cancer is the 2nd leading cause of cancer-related death among women. Increased risk of breast cancer has been associated with high dietary cholesterol intake. However, the underlying mechanisms are not known. The nuclear receptor, estrogen-related receptor alpha (ERRα), plays an important rol...

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Bibliographic Details
Main Authors: Faegheh Ghanbari, Sylvie Mader, Anie Philip
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/8/1765

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