The Overactivation of NADPH Oxidase during <i>Clonorchis sinensis</i> Infection and the Exposure to <i>N</i>-Nitroso Compounds Promote Periductal Fibrosis

The Overactivation of NADPH Oxidase during <i>Clonorchis sinensis</i> Infection and the Exposure to <i>N</i>-Nitroso Compounds Promote Periductal Fibrosis

<i>Clonorchis sinensis</i>, a high-risk pathogenic human liver fluke, provokes various hepatobiliary complications, including epithelial hyperplasia, inflammation, periductal fibrosis, and even cholangiocarcinogenesis via direct contact with worms and their excretory–secretory products (...

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Bibliographic Details
Main Authors: Ji Hoon Jeong, Junyeong Yi, Myung Ki Hwang, Sung-Jong Hong, Woon-Mok Sohn, Tong-Soo Kim, Jhang Ho Pak
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Antioxidants
Subjects:
<i>Clonorchis sinensis</i> infection
excretory-secretory products
<i>N</i>-nitrosodimethylamine
cholangiocytes
oxidative stress
NADPH oxidases
Online Access:https://www.mdpi.com/2076-3921/10/6/869

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