Effect of Nanocrystalline Hydroxyapatite Socket Preservation on Orthodontically Induced Inflammatory Root Resorption
Objective: Orthodontically induced inflammatory root resorption (OIIRR) is considered to be an important sequel associated with orthodontic tooth movement (OTM). OTM after Socket preservation enhances the periodontal condition before orthodontic space closure. The purpose of this study is to investi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Royan Institute (ACECR), Tehran
2015-01-01
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| Series: | Cell Journal |
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| Online Access: | http://celljournal.org/library/upload/article/af_233333362744632563225345222226742432664413-Sara%20Torbati-.pdf |
| _version_ | 1819050003528679424 |
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| author | Massoud Seifi Ali Arayesh Nafise Shamloo Roya Hamedi |
| author_facet | Massoud Seifi Ali Arayesh Nafise Shamloo Roya Hamedi |
| author_sort | Massoud Seifi |
| collection | DOAJ |
| description | Objective: Orthodontically induced inflammatory root resorption (OIIRR) is considered to be an important sequel associated with orthodontic tooth movement (OTM). OTM after Socket preservation enhances the periodontal condition before orthodontic space closure. The purpose of this study is to investigate the histologic effects of NanoBone®, a new highly nonsintered porous nano-crystalline hydroxyapatite bone on root resorption following OTM. Materials and Methods: This experimental study was conducted on four male dogs. In each dog, four defects were created at the mesial aspects of the maxillary and mandibular first premolars. The defects were filled with NanoBone®. We used the NiTi closed coil for mesial movement of the first premolar tooth. When the experimental teeth moved approximately halfway into the defects, after two months, the animals were sacrificed and we harvested the area of interest. The first premolar root and adjacent tissues were histologically evaluated. The three-way ANOVA statistical test was used for comparison. Results: The mean root resorption in the synthetic bone substitute group was 22.87 ± 11.25×10-4 mm2 in the maxilla and 21.41 ± 11.25×10-4 mm2 in the mandible. Statistically, there was no significant difference compared to the control group (p>0.05). Conclusion: The use of a substitution graft in the nano particle has some positive effects in accessing healthy periodontal tissue following orthodontic procedures without significant influence on root resorption (RR). Histological evaluation in the present study showed osteoblastic activity and remodeling environment of nanoparticles in NanoBone®. |
| first_indexed | 2024-12-21T11:41:08Z |
| format | Article |
| id | doaj.art-48f42285c2df44b9b1fdf9f816411f9c |
| institution | Directory Open Access Journal |
| issn | 2228-5806 2228-5814 |
| language | English |
| last_indexed | 2024-12-21T11:41:08Z |
| publishDate | 2015-01-01 |
| publisher | Royan Institute (ACECR), Tehran |
| record_format | Article |
| series | Cell Journal |
| spelling | doaj.art-48f42285c2df44b9b1fdf9f816411f9c2022-12-21T19:05:17ZengRoyan Institute (ACECR), TehranCell Journal2228-58062228-58142015-01-01164514527Effect of Nanocrystalline Hydroxyapatite Socket Preservation on Orthodontically Induced Inflammatory Root ResorptionMassoud Seifi0Ali Arayesh1Nafise Shamloo2Roya Hamedi3Department of Orthodontic, Dentofacial Deformities Research Center , Research Institute of Dental Sciences of Shahid Beheshti University of Medical Sciences, Tehran, IranSchool of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran Department of Oral and Maxillofacial Pathology, Dental School of Shahid Beheshti University of Medical Sciences, Tehran, Iran Department of Orthodontic, Dentofacial Deformity Research Center , School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, IranObjective: Orthodontically induced inflammatory root resorption (OIIRR) is considered to be an important sequel associated with orthodontic tooth movement (OTM). OTM after Socket preservation enhances the periodontal condition before orthodontic space closure. The purpose of this study is to investigate the histologic effects of NanoBone®, a new highly nonsintered porous nano-crystalline hydroxyapatite bone on root resorption following OTM. Materials and Methods: This experimental study was conducted on four male dogs. In each dog, four defects were created at the mesial aspects of the maxillary and mandibular first premolars. The defects were filled with NanoBone®. We used the NiTi closed coil for mesial movement of the first premolar tooth. When the experimental teeth moved approximately halfway into the defects, after two months, the animals were sacrificed and we harvested the area of interest. The first premolar root and adjacent tissues were histologically evaluated. The three-way ANOVA statistical test was used for comparison. Results: The mean root resorption in the synthetic bone substitute group was 22.87 ± 11.25×10-4 mm2 in the maxilla and 21.41 ± 11.25×10-4 mm2 in the mandible. Statistically, there was no significant difference compared to the control group (p>0.05). Conclusion: The use of a substitution graft in the nano particle has some positive effects in accessing healthy periodontal tissue following orthodontic procedures without significant influence on root resorption (RR). Histological evaluation in the present study showed osteoblastic activity and remodeling environment of nanoparticles in NanoBone®.http://celljournal.org/library/upload/article/af_233333362744632563225345222226742432664413-Sara%20Torbati-.pdfHydroxyapatitesNanoparticlesOrthodonticRoot ResorptionTooth MovemenTooth Movement |
| spellingShingle | Massoud Seifi Ali Arayesh Nafise Shamloo Roya Hamedi Effect of Nanocrystalline Hydroxyapatite Socket Preservation on Orthodontically Induced Inflammatory Root Resorption Cell Journal Hydroxyapatites Nanoparticles Orthodontic Root Resorption Tooth Movemen Tooth Movement |
| title | Effect of Nanocrystalline Hydroxyapatite Socket Preservation on Orthodontically Induced Inflammatory Root Resorption |
| title_full | Effect of Nanocrystalline Hydroxyapatite Socket Preservation on Orthodontically Induced Inflammatory Root Resorption |
| title_fullStr | Effect of Nanocrystalline Hydroxyapatite Socket Preservation on Orthodontically Induced Inflammatory Root Resorption |
| title_full_unstemmed | Effect of Nanocrystalline Hydroxyapatite Socket Preservation on Orthodontically Induced Inflammatory Root Resorption |
| title_short | Effect of Nanocrystalline Hydroxyapatite Socket Preservation on Orthodontically Induced Inflammatory Root Resorption |
| title_sort | effect of nanocrystalline hydroxyapatite socket preservation on orthodontically induced inflammatory root resorption |
| topic | Hydroxyapatites Nanoparticles Orthodontic Root Resorption Tooth Movemen Tooth Movement |
| url | http://celljournal.org/library/upload/article/af_233333362744632563225345222226742432664413-Sara%20Torbati-.pdf |
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