Associations of BCL-2 (RS17759659), CTLA-4 (RS231775), APO-1/FAS (RS2234767) genes polymorphisms with activity of proliferation and apoptosis in thyroid tissue of patients with nodular forms of goiter combined with autoimmune thyroiditis and thyroid adenoma

Associations of BCL-2 (RS17759659), CTLA-4 (RS231775), APO-1/FAS (RS2234767) genes polymorphisms with activity of proliferation and apoptosis in thyroid tissue of patients with nodular forms of goiter combined with autoimmune thyroiditis and thyroid adenoma

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The study of apoptosis and proliferative activity in the thyroid gland (TG) tissue of patients with nodular goiter and autoimmune thyroiditis (NGAIT) and thyroid adenoma (TA) is based on the expression/density of Fas/FasL, BCL-2, p53, and Ki-67 markers assessment depending on the genetic polymorphi...

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Bibliographic Details
Main Authors: M. I. Sheremet, L. P. Sydorchuk, V. A. Shidlovskyi, A. D. Bedenyuk, R. I. Sydorchuk, Y. V. Gyrla, O. V. Bilookiy, N. P. Tkachuk, G. S. Kurochkin, A. V. Levitsky
Format: Article
Language:English
Published: Kazimierz Wielki University 2017-08-01
Series:Journal of Education, Health and Sport
Subjects:
nodular goiter with autoimmune thyroiditis
thyroid adenoma
proliferation
apoptosis
APO-1 / FAS
CTLA-4 and BCL-2 genes polymorphisms
Online Access:https://apcz.umk.pl/JEHS/article/view/27446

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