Time for a Drink? A Mathematical Model of Non-human Primate Alcohol Consumption

We simulate a non-human primate's alcohol drinking pattern in order to better understand temporal patterning of alcoholic drinks that can lead to the excessive intakes associated with alcohol use disorder. A stochastic mathematical model of alcohol consumption pattern is developed, where model...

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Bibliographic Details
Main Authors: Sharon Moore, Ami Radunskaya, Elizabeth Zollinger, Kathleen A. Grant, Steven Gonzales, Erich J. Baker
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Applied Mathematics and Statistics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fams.2019.00006/full
Description
Summary:We simulate a non-human primate's alcohol drinking pattern in order to better understand temporal patterning of alcoholic drinks that can lead to the excessive intakes associated with alcohol use disorder. A stochastic mathematical model of alcohol consumption pattern is developed, where model parameters are calibrated to an individual monkey's drinking history. The model predicts a time series that simulates a monkey's alcohol intake in time, and we analyze this drinking pattern to understand the variations in day and night drinking, the lengths of drinks (intake in 5 or more consecutive secs), and lengths of bouts (1 or more drinks per 5 min occasion). This time series can predict a lifetime categorical drinking level (light, binge, heavy, or very heavy), thus correlating an individual monkey's parameters with distinct long term drinking classifications.
ISSN:2297-4687