Time for a Drink? A Mathematical Model of Non-human Primate Alcohol Consumption

We simulate a non-human primate's alcohol drinking pattern in order to better understand temporal patterning of alcoholic drinks that can lead to the excessive intakes associated with alcohol use disorder. A stochastic mathematical model of alcohol consumption pattern is developed, where model...

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Main Authors: Sharon Moore, Ami Radunskaya, Elizabeth Zollinger, Kathleen A. Grant, Steven Gonzales, Erich J. Baker
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Applied Mathematics and Statistics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fams.2019.00006/full
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author Sharon Moore
Ami Radunskaya
Elizabeth Zollinger
Kathleen A. Grant
Steven Gonzales
Erich J. Baker
author_facet Sharon Moore
Ami Radunskaya
Elizabeth Zollinger
Kathleen A. Grant
Steven Gonzales
Erich J. Baker
author_sort Sharon Moore
collection DOAJ
description We simulate a non-human primate's alcohol drinking pattern in order to better understand temporal patterning of alcoholic drinks that can lead to the excessive intakes associated with alcohol use disorder. A stochastic mathematical model of alcohol consumption pattern is developed, where model parameters are calibrated to an individual monkey's drinking history. The model predicts a time series that simulates a monkey's alcohol intake in time, and we analyze this drinking pattern to understand the variations in day and night drinking, the lengths of drinks (intake in 5 or more consecutive secs), and lengths of bouts (1 or more drinks per 5 min occasion). This time series can predict a lifetime categorical drinking level (light, binge, heavy, or very heavy), thus correlating an individual monkey's parameters with distinct long term drinking classifications.
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spelling doaj.art-48f8e7bd8dc0458c976d71c19f5607bb2022-12-21T23:24:36ZengFrontiers Media S.A.Frontiers in Applied Mathematics and Statistics2297-46872019-02-01510.3389/fams.2019.00006407939Time for a Drink? A Mathematical Model of Non-human Primate Alcohol ConsumptionSharon Moore0Ami Radunskaya1Elizabeth Zollinger2Kathleen A. Grant3Steven Gonzales4Erich J. Baker5Department of Computer Science, Bioinformatics, Baylor University, Waco, TX, United StatesDepartment of Mathematics, Pomona College, Claremont, CA, United StatesDepartment of Mathematics and Computer Science, St. Joseph's College, Brooklyn, NY, United StatesOregon Health & Science University, Portland, OR, United StatesOregon Health & Science University, Portland, OR, United StatesDepartment of Computer Science, Bioinformatics, Baylor University, Waco, TX, United StatesWe simulate a non-human primate's alcohol drinking pattern in order to better understand temporal patterning of alcoholic drinks that can lead to the excessive intakes associated with alcohol use disorder. A stochastic mathematical model of alcohol consumption pattern is developed, where model parameters are calibrated to an individual monkey's drinking history. The model predicts a time series that simulates a monkey's alcohol intake in time, and we analyze this drinking pattern to understand the variations in day and night drinking, the lengths of drinks (intake in 5 or more consecutive secs), and lengths of bouts (1 or more drinks per 5 min occasion). This time series can predict a lifetime categorical drinking level (light, binge, heavy, or very heavy), thus correlating an individual monkey's parameters with distinct long term drinking classifications.https://www.frontiersin.org/article/10.3389/fams.2019.00006/fullmathematical modeldrinking classificationMarkov processstochasticmodel fittingalcohol consumption
spellingShingle Sharon Moore
Ami Radunskaya
Elizabeth Zollinger
Kathleen A. Grant
Steven Gonzales
Erich J. Baker
Time for a Drink? A Mathematical Model of Non-human Primate Alcohol Consumption
Frontiers in Applied Mathematics and Statistics
mathematical model
drinking classification
Markov process
stochastic
model fitting
alcohol consumption
title Time for a Drink? A Mathematical Model of Non-human Primate Alcohol Consumption
title_full Time for a Drink? A Mathematical Model of Non-human Primate Alcohol Consumption
title_fullStr Time for a Drink? A Mathematical Model of Non-human Primate Alcohol Consumption
title_full_unstemmed Time for a Drink? A Mathematical Model of Non-human Primate Alcohol Consumption
title_short Time for a Drink? A Mathematical Model of Non-human Primate Alcohol Consumption
title_sort time for a drink a mathematical model of non human primate alcohol consumption
topic mathematical model
drinking classification
Markov process
stochastic
model fitting
alcohol consumption
url https://www.frontiersin.org/article/10.3389/fams.2019.00006/full
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