Neutralizing a Springboard for Inflammation: Physical Activity to Control the Immune Network

The severe consequences of the present Corona Virus Disease 2019 COVID-19 pandemic seem to be closely related to an already ongoing (‘first’) pandemic, directly associated with a sedentary lifestyle. It seems evident that the prognosis after infection is substantially worse for individuals suffering...

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Main Authors: Victor Kallen, Rogier Scherder, Maarten J. Cramer, Jacqueline Stam, Bruce Johnson, Erik Scherder
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Healthcare
Subjects:
Online Access:https://www.mdpi.com/2227-9032/9/9/1196
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author Victor Kallen
Rogier Scherder
Maarten J. Cramer
Jacqueline Stam
Bruce Johnson
Erik Scherder
author_facet Victor Kallen
Rogier Scherder
Maarten J. Cramer
Jacqueline Stam
Bruce Johnson
Erik Scherder
author_sort Victor Kallen
collection DOAJ
description The severe consequences of the present Corona Virus Disease 2019 COVID-19 pandemic seem to be closely related to an already ongoing (‘first’) pandemic, directly associated with a sedentary lifestyle. It seems evident that the prognosis after infection is substantially worse for individuals suffering from, for example, (visceral) obesity, cardiovascular disease, and diabetes type 2. Consequently, it may be considered highly relevant to gain insight into the potential beneficial effects of exercise interventions to strengthen the immune system, particularly in high-risk populations. For this reason, the exercise protocols that are suggested to strengthen the immune system, which can be executed by all ages and almost all physical conditions, were reviewed and evaluated. Previously published protocols range from interrupting prolonged sitting, to regular low-to-moderate exercise activities, to high intensity, typically interval, sports formats. Reported positive effects on immune functioning appear to be induced either directly or via beneficial metabolic and/or psychological effects and become measurable after 3 weeks to 3 months. Based in these findings, it appeared possible to design an optimal exercise protocol to maximize effects on immune functioning that should be executable for all, even under restricted (‘lockdown’) circumstances.
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spelling doaj.art-48fa2ebe098a4804bfbf88fe1f7b3c572023-11-22T13:18:24ZengMDPI AGHealthcare2227-90322021-09-0199119610.3390/healthcare9091196Neutralizing a Springboard for Inflammation: Physical Activity to Control the Immune NetworkVictor Kallen0Rogier Scherder1Maarten J. Cramer2Jacqueline Stam3Bruce Johnson4Erik Scherder5The Netherlands Organization for Applied Sciences (TNO), P.O. Box 23, 3769 ZG Soesterberg, The NetherlandsDepartment of Sports Medicine, University Medical Center Utrecht, Heidelberglaan 8, 3584 CS Utrecht, The NetherlandsDepartment of Cardiology, University Medical Center Utrecht, Heidelberglaan 8, 3584 CS Utrecht, The NetherlandsThe Netherlands Organization for Applied Sciences (TNO), P.O. Box 23, 3769 ZG Soesterberg, The NetherlandsDepartment of Cardiovascular Medicine, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USADepartment of Clinical Neuropsychology, Vrije Universiteit Amsterdam, De Boelelaan 1105, 1081 HV Amsterdam, The NetherlandsThe severe consequences of the present Corona Virus Disease 2019 COVID-19 pandemic seem to be closely related to an already ongoing (‘first’) pandemic, directly associated with a sedentary lifestyle. It seems evident that the prognosis after infection is substantially worse for individuals suffering from, for example, (visceral) obesity, cardiovascular disease, and diabetes type 2. Consequently, it may be considered highly relevant to gain insight into the potential beneficial effects of exercise interventions to strengthen the immune system, particularly in high-risk populations. For this reason, the exercise protocols that are suggested to strengthen the immune system, which can be executed by all ages and almost all physical conditions, were reviewed and evaluated. Previously published protocols range from interrupting prolonged sitting, to regular low-to-moderate exercise activities, to high intensity, typically interval, sports formats. Reported positive effects on immune functioning appear to be induced either directly or via beneficial metabolic and/or psychological effects and become measurable after 3 weeks to 3 months. Based in these findings, it appeared possible to design an optimal exercise protocol to maximize effects on immune functioning that should be executable for all, even under restricted (‘lockdown’) circumstances.https://www.mdpi.com/2227-9032/9/9/1196COVID-19exercisestressimmune functioninginflammationsedentary
spellingShingle Victor Kallen
Rogier Scherder
Maarten J. Cramer
Jacqueline Stam
Bruce Johnson
Erik Scherder
Neutralizing a Springboard for Inflammation: Physical Activity to Control the Immune Network
Healthcare
COVID-19
exercise
stress
immune functioning
inflammation
sedentary
title Neutralizing a Springboard for Inflammation: Physical Activity to Control the Immune Network
title_full Neutralizing a Springboard for Inflammation: Physical Activity to Control the Immune Network
title_fullStr Neutralizing a Springboard for Inflammation: Physical Activity to Control the Immune Network
title_full_unstemmed Neutralizing a Springboard for Inflammation: Physical Activity to Control the Immune Network
title_short Neutralizing a Springboard for Inflammation: Physical Activity to Control the Immune Network
title_sort neutralizing a springboard for inflammation physical activity to control the immune network
topic COVID-19
exercise
stress
immune functioning
inflammation
sedentary
url https://www.mdpi.com/2227-9032/9/9/1196
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AT jacquelinestam neutralizingaspringboardforinflammationphysicalactivitytocontroltheimmunenetwork
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AT erikscherder neutralizingaspringboardforinflammationphysicalactivitytocontroltheimmunenetwork