Retrospective study of clinic-epidemiological correlation between body mass index (BMI) and colorectal cancer (CRC) with survival impact
Background: Body mass index (BMI) is positively associated with the risk of colorectal cancer (CRC). For that reason, investigators have hypothesized that being overweight or obese leads to worse CRC prognosis and survival outcome. Methodology: The impact of BMI in patients with colorectal cancer on...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Cancer Treatment and Research Communications |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468294222001137 |
| _version_ | 1817999541682569216 |
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| author | Doaa Atef Mohamed Soliman |
| author_facet | Doaa Atef Mohamed Soliman |
| author_sort | Doaa Atef Mohamed Soliman |
| collection | DOAJ |
| description | Background: Body mass index (BMI) is positively associated with the risk of colorectal cancer (CRC). For that reason, investigators have hypothesized that being overweight or obese leads to worse CRC prognosis and survival outcome. Methodology: The impact of BMI in patients with colorectal cancer on (disease free survival) DFS and three years overall survival (OS) rates in correlation with clinic-pathological data of those patients was studied on 128 patients enrolled in this study. They were diagnosed with stage II and III colorectal cancer that presented at clinical oncology department Ain Shams University hospitals from January 2016 till December 2017 with 3 years duration follow up. All of them had measured their BMI at time of presentation. Results: Estimated 3- years OS for each BMI category revealed that normal weight patients had 97.1% survival rate and overweight patients had 77.8% survival rate. Much lower survival rates for both underweight and obese patients had been estimated being (33.3%, 37.3%) respectively. This correlation to BMI categories shows a statistically significant value between normal weight patients and overweight patients in relation to underweight and obese patients (p- value < 0.0001). Conclusion: BMI has an impact on colorectal cancer patients with clinicopathological relations and survival rate. |
| first_indexed | 2024-04-14T03:10:18Z |
| format | Article |
| id | doaj.art-49000412cf1040a4bdffb5f042afb2d1 |
| institution | Directory Open Access Journal |
| issn | 2468-2942 |
| language | English |
| last_indexed | 2024-04-14T03:10:18Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Cancer Treatment and Research Communications |
| spelling | doaj.art-49000412cf1040a4bdffb5f042afb2d12022-12-22T02:15:36ZengElsevierCancer Treatment and Research Communications2468-29422022-01-0132100622Retrospective study of clinic-epidemiological correlation between body mass index (BMI) and colorectal cancer (CRC) with survival impactDoaa Atef Mohamed Soliman0Clinical Oncology Department, Faculty of Medicine, Ain Shams University El-Abbassia square, Ahmed Lotfy El Sayed Street Cairo, EgyptBackground: Body mass index (BMI) is positively associated with the risk of colorectal cancer (CRC). For that reason, investigators have hypothesized that being overweight or obese leads to worse CRC prognosis and survival outcome. Methodology: The impact of BMI in patients with colorectal cancer on (disease free survival) DFS and three years overall survival (OS) rates in correlation with clinic-pathological data of those patients was studied on 128 patients enrolled in this study. They were diagnosed with stage II and III colorectal cancer that presented at clinical oncology department Ain Shams University hospitals from January 2016 till December 2017 with 3 years duration follow up. All of them had measured their BMI at time of presentation. Results: Estimated 3- years OS for each BMI category revealed that normal weight patients had 97.1% survival rate and overweight patients had 77.8% survival rate. Much lower survival rates for both underweight and obese patients had been estimated being (33.3%, 37.3%) respectively. This correlation to BMI categories shows a statistically significant value between normal weight patients and overweight patients in relation to underweight and obese patients (p- value < 0.0001). Conclusion: BMI has an impact on colorectal cancer patients with clinicopathological relations and survival rate.http://www.sciencedirect.com/science/article/pii/S2468294222001137Body mass indexColorectal cancer (CRC)Disease- free survival (DFS)Overall survival (OS) |
| spellingShingle | Doaa Atef Mohamed Soliman Retrospective study of clinic-epidemiological correlation between body mass index (BMI) and colorectal cancer (CRC) with survival impact Cancer Treatment and Research Communications Body mass index Colorectal cancer (CRC) Disease- free survival (DFS) Overall survival (OS) |
| title | Retrospective study of clinic-epidemiological correlation between body mass index (BMI) and colorectal cancer (CRC) with survival impact |
| title_full | Retrospective study of clinic-epidemiological correlation between body mass index (BMI) and colorectal cancer (CRC) with survival impact |
| title_fullStr | Retrospective study of clinic-epidemiological correlation between body mass index (BMI) and colorectal cancer (CRC) with survival impact |
| title_full_unstemmed | Retrospective study of clinic-epidemiological correlation between body mass index (BMI) and colorectal cancer (CRC) with survival impact |
| title_short | Retrospective study of clinic-epidemiological correlation between body mass index (BMI) and colorectal cancer (CRC) with survival impact |
| title_sort | retrospective study of clinic epidemiological correlation between body mass index bmi and colorectal cancer crc with survival impact |
| topic | Body mass index Colorectal cancer (CRC) Disease- free survival (DFS) Overall survival (OS) |
| url | http://www.sciencedirect.com/science/article/pii/S2468294222001137 |
| work_keys_str_mv | AT doaaatefmohamedsoliman retrospectivestudyofclinicepidemiologicalcorrelationbetweenbodymassindexbmiandcolorectalcancercrcwithsurvivalimpact |