The Reticulon-4 3-bp Deletion/Insertion Polymorphism Is Associated with Structural mRNA Changes and the Risk of Breast Cancer: A Population-Based Case–Control Study with Bioinformatics Analysis

The Reticulon-4 3-bp Deletion/Insertion Polymorphism Is Associated with Structural mRNA Changes and the Risk of Breast Cancer: A Population-Based Case–Control Study with Bioinformatics Analysis

Breast cancer (BC) is a complex disease caused by molecular events that disrupt cellular survival and death. Discovering novel biomarkers is still required to better understand and treat BC. The reticulon-4 (RTN4) gene, encoding Nogo proteins, plays a critical role in apoptosis and cancer developmen...

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Bibliographic Details
Main Authors: Pouria Pourzand, Farhad Tabasi, Fariba Fayazbakhsh, Shamim Sarhadi, Gholamreza Bahari, Mohsen Mohammadi, Sahar Jomepour, Mohammad Nafeli, Fatemeh Mosayebi, Mehrdad Heravi, Mohsen Taheri, Mohammad Hashemi, Saeid Ghavami
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Life
Subjects:
RTN4
rs34917480
polymorphism
breast cancer
Online Access:https://www.mdpi.com/2075-1729/13/7/1549

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