Chemomimesis and Molecular Darwinism in Action: From Abiotic Generation of Nucleobases to Nucleosides and RNA
Molecular Darwinian evolution is an intrinsic property of reacting pools of molecules resulting in the adaptation of the system to changing conditions. It has no a priori aim. From the point of view of the origin of life, Darwinian selection behavior, when spontaneously emerging in the ensembles of...
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MDPI AG
2018-06-01
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| Series: | Life |
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| Online Access: | http://www.mdpi.com/2075-1729/8/2/24 |
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| author | Raffaele Saladino Judit E. Šponer Jiří Šponer Giovanna Costanzo Samanta Pino Ernesto Di Mauro |
| author_facet | Raffaele Saladino Judit E. Šponer Jiří Šponer Giovanna Costanzo Samanta Pino Ernesto Di Mauro |
| author_sort | Raffaele Saladino |
| collection | DOAJ |
| description | Molecular Darwinian evolution is an intrinsic property of reacting pools of molecules resulting in the adaptation of the system to changing conditions. It has no a priori aim. From the point of view of the origin of life, Darwinian selection behavior, when spontaneously emerging in the ensembles of molecules composing prebiotic pools, initiates subsequent evolution of increasingly complex and innovative chemical information. On the conservation side, it is a posteriori observed that numerous biological processes are based on prebiotically promptly made compounds, as proposed by the concept of Chemomimesis. Molecular Darwinian evolution and Chemomimesis are principles acting in balanced cooperation in the frame of Systems Chemistry. The one-pot synthesis of nucleosides in radical chemistry conditions is possibly a telling example of the operation of these principles. Other indications of similar cases of molecular evolution can be found among biogenic processes. |
| first_indexed | 2024-04-11T12:18:08Z |
| format | Article |
| id | doaj.art-49038e57b682405b84a42d9c721972c6 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-04-11T12:18:08Z |
| publishDate | 2018-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-49038e57b682405b84a42d9c721972c62022-12-22T04:24:12ZengMDPI AGLife2075-17292018-06-01822410.3390/life8020024life8020024Chemomimesis and Molecular Darwinism in Action: From Abiotic Generation of Nucleobases to Nucleosides and RNARaffaele Saladino0Judit E. Šponer1Jiří Šponer2Giovanna Costanzo3Samanta Pino4Ernesto Di Mauro5Biological and Ecological Department, University of Tuscia, 01100 Viterbo, ItalyInstitute of Biophysics of the Czech Academy of Sciences, Královopolská 135, 61265 Brno, Czech RepublicInstitute of Biophysics of the Czech Academy of Sciences, Královopolská 135, 61265 Brno, Czech RepublicInstitute of Molecular Biology and Pathology, CNR, 00185 Rome, ItalyBiological and Ecological Department, University of Tuscia, 01100 Viterbo, ItalyBiological and Ecological Department, University of Tuscia, 01100 Viterbo, ItalyMolecular Darwinian evolution is an intrinsic property of reacting pools of molecules resulting in the adaptation of the system to changing conditions. It has no a priori aim. From the point of view of the origin of life, Darwinian selection behavior, when spontaneously emerging in the ensembles of molecules composing prebiotic pools, initiates subsequent evolution of increasingly complex and innovative chemical information. On the conservation side, it is a posteriori observed that numerous biological processes are based on prebiotically promptly made compounds, as proposed by the concept of Chemomimesis. Molecular Darwinian evolution and Chemomimesis are principles acting in balanced cooperation in the frame of Systems Chemistry. The one-pot synthesis of nucleosides in radical chemistry conditions is possibly a telling example of the operation of these principles. Other indications of similar cases of molecular evolution can be found among biogenic processes.http://www.mdpi.com/2075-1729/8/2/24origin of lifesystems chemistryChemomimesisMolecular Darwinism |
| spellingShingle | Raffaele Saladino Judit E. Šponer Jiří Šponer Giovanna Costanzo Samanta Pino Ernesto Di Mauro Chemomimesis and Molecular Darwinism in Action: From Abiotic Generation of Nucleobases to Nucleosides and RNA Life origin of life systems chemistry Chemomimesis Molecular Darwinism |
| title | Chemomimesis and Molecular Darwinism in Action: From Abiotic Generation of Nucleobases to Nucleosides and RNA |
| title_full | Chemomimesis and Molecular Darwinism in Action: From Abiotic Generation of Nucleobases to Nucleosides and RNA |
| title_fullStr | Chemomimesis and Molecular Darwinism in Action: From Abiotic Generation of Nucleobases to Nucleosides and RNA |
| title_full_unstemmed | Chemomimesis and Molecular Darwinism in Action: From Abiotic Generation of Nucleobases to Nucleosides and RNA |
| title_short | Chemomimesis and Molecular Darwinism in Action: From Abiotic Generation of Nucleobases to Nucleosides and RNA |
| title_sort | chemomimesis and molecular darwinism in action from abiotic generation of nucleobases to nucleosides and rna |
| topic | origin of life systems chemistry Chemomimesis Molecular Darwinism |
| url | http://www.mdpi.com/2075-1729/8/2/24 |
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