Transplantation of intestinal microbiota

The results are presented of evaluation of the efficiency of the filtered aqueous suspension of white mice (donors) feces and microorganisms of indigenous microflora in the correction of intestinal microbiocenosis of conventional white mice with antibiotic-associated dysbacteriosis with administrati...

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Main Authors: I. Yu. Chicherin, I. P. Pogorelskiy, I. A. Lundovskikh, M. R. Shabalina, I. V. Darmov
Format: Article
Language:Russian
Published: Journal Infectology 2014-09-01
Series:Журнал инфектологии
Subjects:
Online Access:https://journal.niidi.ru/jofin/article/view/174
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author I. Yu. Chicherin
I. P. Pogorelskiy
I. A. Lundovskikh
M. R. Shabalina
I. V. Darmov
author_facet I. Yu. Chicherin
I. P. Pogorelskiy
I. A. Lundovskikh
M. R. Shabalina
I. V. Darmov
author_sort I. Yu. Chicherin
collection DOAJ
description The results are presented of evaluation of the efficiency of the filtered aqueous suspension of white mice (donors) feces and microorganisms of indigenous microflora in the correction of intestinal microbiocenosis of conventional white mice with antibiotic-associated dysbacteriosis with administration of suspension and microorganisms per os and per rectum. After the start of administration of suspension and microorganisms of fecal microflora to experimental animals the dynamics of the total content of microorganisms and the number of some representatives of intestinal microflora in 1 g of feces were evaluated in comparison with self-recovery of intestinal microflora in the control group animals. Results showed that the supernatant of an aqueous suspension of white mice (donors) feces, containing microbial exometabolites and other biologically active compounds, has in a short time the most pronounced effect on the recovery of the normal intestinal microflora in experimental animals.
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spelling doaj.art-49040085808d43f7ac30570940e1d9632025-03-02T13:00:24ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-0152828910.22625/2072-6732-2013-5-2-82-89188Transplantation of intestinal microbiotaI. Yu. Chicherin0I. P. Pogorelskiy1I. A. Lundovskikh2M. R. Shabalina3I. V. Darmov4Scientific society «Microbiota», Sergiev PosadVyatka State University, KirovСогласноVyatka State University, KirovСогласноVyatka State University, KirovСогласноVyatka State University, KirovСогласноThe results are presented of evaluation of the efficiency of the filtered aqueous suspension of white mice (donors) feces and microorganisms of indigenous microflora in the correction of intestinal microbiocenosis of conventional white mice with antibiotic-associated dysbacteriosis with administration of suspension and microorganisms per os and per rectum. After the start of administration of suspension and microorganisms of fecal microflora to experimental animals the dynamics of the total content of microorganisms and the number of some representatives of intestinal microflora in 1 g of feces were evaluated in comparison with self-recovery of intestinal microflora in the control group animals. Results showed that the supernatant of an aqueous suspension of white mice (donors) feces, containing microbial exometabolites and other biologically active compounds, has in a short time the most pronounced effect on the recovery of the normal intestinal microflora in experimental animals.https://journal.niidi.ru/jofin/article/view/174exometabolitesintestinal microfloradysbacteriosistransplantation of intestinal microbiota
spellingShingle I. Yu. Chicherin
I. P. Pogorelskiy
I. A. Lundovskikh
M. R. Shabalina
I. V. Darmov
Transplantation of intestinal microbiota
Журнал инфектологии
exometabolites
intestinal microflora
dysbacteriosis
transplantation of intestinal microbiota
title Transplantation of intestinal microbiota
title_full Transplantation of intestinal microbiota
title_fullStr Transplantation of intestinal microbiota
title_full_unstemmed Transplantation of intestinal microbiota
title_short Transplantation of intestinal microbiota
title_sort transplantation of intestinal microbiota
topic exometabolites
intestinal microflora
dysbacteriosis
transplantation of intestinal microbiota
url https://journal.niidi.ru/jofin/article/view/174
work_keys_str_mv AT iyuchicherin transplantationofintestinalmicrobiota
AT ippogorelskiy transplantationofintestinalmicrobiota
AT ialundovskikh transplantationofintestinalmicrobiota
AT mrshabalina transplantationofintestinalmicrobiota
AT ivdarmov transplantationofintestinalmicrobiota