Limited Association between Schizophrenia Genetic Risk Factors and Transcriptomic Features

Limited Association between Schizophrenia Genetic Risk Factors and Transcriptomic Features

Schizophrenia is a polygenic disorder with many genomic regions contributing to schizophrenia risk. The majority of genetic variants associated with schizophrenia lie in the non-coding genome and are thought to contribute to transcriptional regulation. Extensive transcriptomic dysregulation has been...

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Bibliographic Details
Main Authors: Alice W. Yu, J. David Peery, Hyejung Won
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Genes
Subjects:
schizophrenia
GWAS
LD score regression
differentially expressed genes
co-expression networks
transcriptional regulation
Online Access:https://www.mdpi.com/2073-4425/12/7/1062

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