Establishment of a human iPSC line (SUTCMi001-A) derived from a healthy donor
This study describes the characterization of one induced pluripotent stem cell line (iPSC) from a healthy female. It is crucial to use iPSCs derived from healthy individuals as controls in genetic disease studies. Thus, we established a human iPSC cell line derived from healthy people. The iPSC cell...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-08-01
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| Series: | Stem Cell Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506122001982 |
| _version_ | 1818010992423993344 |
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| author | Lingyuan Min Yongtian Yin Qingyang Zhao Shiyuan Wang |
| author_facet | Lingyuan Min Yongtian Yin Qingyang Zhao Shiyuan Wang |
| author_sort | Lingyuan Min |
| collection | DOAJ |
| description | This study describes the characterization of one induced pluripotent stem cell line (iPSC) from a healthy female. It is crucial to use iPSCs derived from healthy individuals as controls in genetic disease studies. Thus, we established a human iPSC cell line derived from healthy people. The iPSC cell line was generated in our lab from the peripheral blood mononuclear cells (PBMCs) of a 28-year-old girl. The generated hiPSC line is free of episomal vectors, has a normal karyotype, expresses pluripotency markers and can differentiate into three germ layers in vivo. |
| first_indexed | 2024-04-14T06:01:37Z |
| format | Article |
| id | doaj.art-4906c283994f4e4285a755f9a8b53e08 |
| institution | Directory Open Access Journal |
| issn | 1873-5061 |
| language | English |
| last_indexed | 2024-04-14T06:01:37Z |
| publishDate | 2022-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Stem Cell Research |
| spelling | doaj.art-4906c283994f4e4285a755f9a8b53e082022-12-22T02:08:43ZengElsevierStem Cell Research1873-50612022-08-0163102849Establishment of a human iPSC line (SUTCMi001-A) derived from a healthy donorLingyuan Min0Yongtian Yin1Qingyang Zhao2Shiyuan Wang3Research Center of Translational Medicine, Central Hospital Affiliated to Shandong First Medical University, Ji’nan 250013, Shandong, ChinaShandong University of Traditional Chinese Medicine, Ji’nan 250355, Shandong, ChinaShandong University of Traditional Chinese Medicine, Ji’nan 250355, Shandong, China; Corresponding authors.Shandong University of Traditional Chinese Medicine, Ji’nan 250355, Shandong, China; Corresponding authors.This study describes the characterization of one induced pluripotent stem cell line (iPSC) from a healthy female. It is crucial to use iPSCs derived from healthy individuals as controls in genetic disease studies. Thus, we established a human iPSC cell line derived from healthy people. The iPSC cell line was generated in our lab from the peripheral blood mononuclear cells (PBMCs) of a 28-year-old girl. The generated hiPSC line is free of episomal vectors, has a normal karyotype, expresses pluripotency markers and can differentiate into three germ layers in vivo.http://www.sciencedirect.com/science/article/pii/S1873506122001982 |
| spellingShingle | Lingyuan Min Yongtian Yin Qingyang Zhao Shiyuan Wang Establishment of a human iPSC line (SUTCMi001-A) derived from a healthy donor Stem Cell Research |
| title | Establishment of a human iPSC line (SUTCMi001-A) derived from a healthy donor |
| title_full | Establishment of a human iPSC line (SUTCMi001-A) derived from a healthy donor |
| title_fullStr | Establishment of a human iPSC line (SUTCMi001-A) derived from a healthy donor |
| title_full_unstemmed | Establishment of a human iPSC line (SUTCMi001-A) derived from a healthy donor |
| title_short | Establishment of a human iPSC line (SUTCMi001-A) derived from a healthy donor |
| title_sort | establishment of a human ipsc line sutcmi001 a derived from a healthy donor |
| url | http://www.sciencedirect.com/science/article/pii/S1873506122001982 |
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