Senescence of Tumor Cells in Anticancer Therapy—Beneficial and Detrimental Effects

Senescence of Tumor Cells in Anticancer Therapy—Beneficial and Detrimental Effects

Cellular senescence process results in stable cell cycle arrest, which prevents cell proliferation. It can be induced by a variety of stimuli including metabolic stress, DNA damage, telomeres shortening, and oncogenes activation. Senescence is generally considered as a process of tumor suppression,...

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Bibliographic Details
Main Authors: Wiktoria Monika Piskorz, Marzanna Cechowska-Pasko
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
senescence
cancer
therapy
senolysis
senolytics
senostatics
Online Access:https://www.mdpi.com/1422-0067/23/19/11082

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