Causal associations between risk factors and common diseases inferred from GWAS summary data
Genetic methods are useful to test whether risk factors are causal for or consequence of disease. Here, Zhu et al. develop a generalized summary-based Mendelian Randomization (GSMR) method which uses summary-level data from GWAS to test for causal associations of health risk factors with common dise...
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Bibliographic Details
| Main Authors: |
Zhihong Zhu,
Zhili Zheng,
Futao Zhang,
Yang Wu,
Maciej Trzaskowski,
Robert Maier,
Matthew R. Robinson,
John J. McGrath,
Peter M. Visscher,
Naomi R. Wray,
Jian Yang |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2018-01-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-017-02317-2
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