PDGF-loaded microneedles promote tendon healing through p38/cyclin D1 pathway mediated angiogenesis

PDGF-loaded microneedles promote tendon healing through p38/cyclin D1 pathway mediated angiogenesis

Tendon injury is one of the most serious orthopedic diseases often leading to disability of patients. Major shortages of tendon healing are due to its multiple comorbidities, uncertainty of therapeutic efficacy and insufficient of angiogenesis. With a deeper understanding of angiogenic mechanism of...

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Bibliographic Details
Main Authors: Xuanzhe Liu, Yuange Li, Shuo Wang, Mingkuan Lu, Jian Zou, Zhongmin Shi, Binbin Xu, Wei Wang, Bo Hu, Tuo Jin, Fei Wu, Shen Liu, Cunyi Fan
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Materials Today Bio
Subjects:
PDGF
Microneedle
Tendon healing
p38/cyclin D1 pathway
Angiogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006422002265

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