Mask and Release Strategy‐Enabled Diversity‐Oriented Synthesis for DNA‐Encoded Library
Abstract An ideal DNA‐encoded library (DEL) selection requires the library to consist of diverse core skeletons and cover chemical space as much as possible. However, the lack of efficient on‐DNA synthetic approaches toward core skeletons has greatly restricted the diversity of DEL. To mitigate this...
Main Authors: | Silin Zhang, Haiman Zhang, Xiawen Liu, Ping Qi, Tingting Tan, Shengdong Wang, Hui Gao, Hongtao Xu, Zhi Zhou, Wei Yi |
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Format: | Article |
Language: | English |
Published: |
Wiley
2024-02-01
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Series: | Advanced Science |
Subjects: | |
Online Access: | https://doi.org/10.1002/advs.202307049 |
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