Mask and Release Strategy‐Enabled Diversity‐Oriented Synthesis for DNA‐Encoded Library

Mask and Release Strategy‐Enabled Diversity‐Oriented Synthesis for DNA‐Encoded Library

Abstract An ideal DNA‐encoded library (DEL) selection requires the library to consist of diverse core skeletons and cover chemical space as much as possible. However, the lack of efficient on‐DNA synthetic approaches toward core skeletons has greatly restricted the diversity of DEL. To mitigate this...

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Bibliographic Details
Main Authors: Silin Zhang, Haiman Zhang, Xiawen Liu, Ping Qi, Tingting Tan, Shengdong Wang, Hui Gao, Hongtao Xu, Zhi Zhou, Wei Yi
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Advanced Science
Subjects:
benzofuran
diversity‐oriented synthesis
DNA‐encoded library
mask and release
sulfiliminyl phenol
Online Access:https://doi.org/10.1002/advs.202307049

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