A New Approach to Developing Long-Acting Injectable Formulations of Anti-HIV Drugs: Poly(Ethylene Phosphoric Acid) Block Copolymers Increase the Efficiency of Tenofovir against HIV-1 in MT-4 Cells

A New Approach to Developing Long-Acting Injectable Formulations of Anti-HIV Drugs: Poly(Ethylene Phosphoric Acid) Block Copolymers Increase the Efficiency of Tenofovir against HIV-1 in MT-4 Cells

Despite the world’s combined efforts, human immunodeficiency virus (HIV), the causative agent of AIDS, remains one of the world’s most serious public health challenges. High genetic variability of HIV complicates the development of anti-HIV vaccine, and there is an actual clinical need for increasin...

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Bibliographic Details
Main Authors: Ilya Nifant’ev, Andrei Siniavin, Eduard Karamov, Maxim Kosarev, Sergey Kovalchuk, Ali Turgiev, Sergey Nametkin, Vladimir Bagrov, Alexander Tavtorkin, Pavel Ivchenko
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
AIDS
cART
controlled release
HIV
injectable formulations
long-acting drugs
Online Access:https://www.mdpi.com/1422-0067/22/1/340

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