Expression levels of a gene signature in hiPSC associated with lung adenocarcinoma stem cells and its capability in eliciting specific antitumor immune‐response in a humanized mice model

Expression levels of a gene signature in hiPSC associated with lung adenocarcinoma stem cells and its capability in eliciting specific antitumor immune‐response in a humanized mice model

Background Previous studies have reported that cancer stem cells (CSCs) play a key role in tumorigenesis, metastasis, and recurrence. CSC‐based vaccination confers better protection in tumor cells. However, isolation and cultivation of CSCs are difficult. This study aimed to explore the similarities...

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Bibliographic Details
Main Authors: Jingbo Wang, Lijuan Shao, Liujing Wu, Wei Ma, Yuanyuan Zheng, Chaofeng Hu, Furong Li
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Thoracic Cancer
Subjects:
Cancer stem cell
hiPSC
humanize mice model
immune response
tumor vaccine
Online Access:https://doi.org/10.1111/1759-7714.13440

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