Cardiopulmonary Exercise Performance of Children Born Non-Extremely Preterm
Data on exercise tolerance of children born non-extremely preterm are sparse. We aimed to explore the cardiopulmonary exercise testing (CPET) characteristics in this population. We studied 63 children (age 7–12 years) born at 29<sup>0/7</sup>–36<sup>6/7</sup> weeks of gestati...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/11/2/198 |
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| author | Sotirios Fouzas Aikaterini Nourloglou Aggeliki Vervenioti Ageliki Karatza Michael B. Anthracopoulos Gabriel Dimitriou |
| author_facet | Sotirios Fouzas Aikaterini Nourloglou Aggeliki Vervenioti Ageliki Karatza Michael B. Anthracopoulos Gabriel Dimitriou |
| author_sort | Sotirios Fouzas |
| collection | DOAJ |
| description | Data on exercise tolerance of children born non-extremely preterm are sparse. We aimed to explore the cardiopulmonary exercise testing (CPET) characteristics in this population. We studied 63 children (age 7–12 years) born at 29<sup>0/7</sup>–36<sup>6/7</sup> weeks of gestation (34 were late preterm, 29 were preterm) and 63 age-matched, term-born controls. All performed spirometry and CPET (cycle ergometry). There were no differences in activity levels and spirometric parameters between the group of preterm-born children and controls. A peak oxygen uptake (VO<sub>2</sub>peak) of <80% was noted in 25.4% of the term-born and 49.2% of preterm-born children (<i>p</i> = 0.001). Term-born participants presented similar VO<sub>2</sub>peak to late-preterm children but higher than those born at <34<sup>0/7</sup> weeks of gestation (<i>p</i> = 0.002). Ventilatory limitation was noted in 4.8% of term and 7.9% of preterm participants, while only one preterm child presented cardiovascular limitation. Children born before 34 weeks of gestation had higher respiratory rates and smaller tidal volumes at maximum exercise, as well as lower oxygen uptake for the level of generated work. We conclude that school-age children born at 29–34 weeks of gestation may present decreased exercise performance attributed to an altered ventilatory response to exercise and impaired O<sub>2</sub> utilization by their skeletal muscles rather than other cardiopulmonary limiting factors. |
| first_indexed | 2024-03-07T22:37:32Z |
| format | Article |
| id | doaj.art-491c8bb708a342a8993e858ef93679ab |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-07T22:37:32Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-491c8bb708a342a8993e858ef93679ab2024-02-23T15:12:22ZengMDPI AGChildren2227-90672024-02-0111219810.3390/children11020198Cardiopulmonary Exercise Performance of Children Born Non-Extremely PretermSotirios Fouzas0Aikaterini Nourloglou1Aggeliki Vervenioti2Ageliki Karatza3Michael B. Anthracopoulos4Gabriel Dimitriou5Department of Pediatrics, University of Patras School of Medicine, 26504 Patras, GreeceDepartment of Pediatrics, University of Patras School of Medicine, 26504 Patras, GreeceDepartment of Pediatrics, University of Patras School of Medicine, 26504 Patras, GreeceDepartment of Pediatrics, University of Patras School of Medicine, 26504 Patras, GreeceDepartment of Pediatrics, University of Patras School of Medicine, 26504 Patras, GreeceDepartment of Pediatrics, University of Patras School of Medicine, 26504 Patras, GreeceData on exercise tolerance of children born non-extremely preterm are sparse. We aimed to explore the cardiopulmonary exercise testing (CPET) characteristics in this population. We studied 63 children (age 7–12 years) born at 29<sup>0/7</sup>–36<sup>6/7</sup> weeks of gestation (34 were late preterm, 29 were preterm) and 63 age-matched, term-born controls. All performed spirometry and CPET (cycle ergometry). There were no differences in activity levels and spirometric parameters between the group of preterm-born children and controls. A peak oxygen uptake (VO<sub>2</sub>peak) of <80% was noted in 25.4% of the term-born and 49.2% of preterm-born children (<i>p</i> = 0.001). Term-born participants presented similar VO<sub>2</sub>peak to late-preterm children but higher than those born at <34<sup>0/7</sup> weeks of gestation (<i>p</i> = 0.002). Ventilatory limitation was noted in 4.8% of term and 7.9% of preterm participants, while only one preterm child presented cardiovascular limitation. Children born before 34 weeks of gestation had higher respiratory rates and smaller tidal volumes at maximum exercise, as well as lower oxygen uptake for the level of generated work. We conclude that school-age children born at 29–34 weeks of gestation may present decreased exercise performance attributed to an altered ventilatory response to exercise and impaired O<sub>2</sub> utilization by their skeletal muscles rather than other cardiopulmonary limiting factors.https://www.mdpi.com/2227-9067/11/2/198cardiopulmonary exercise testingexercise performanceexercise toleranceprematuritypreterm childrenchildren |
| spellingShingle | Sotirios Fouzas Aikaterini Nourloglou Aggeliki Vervenioti Ageliki Karatza Michael B. Anthracopoulos Gabriel Dimitriou Cardiopulmonary Exercise Performance of Children Born Non-Extremely Preterm Children cardiopulmonary exercise testing exercise performance exercise tolerance prematurity preterm children children |
| title | Cardiopulmonary Exercise Performance of Children Born Non-Extremely Preterm |
| title_full | Cardiopulmonary Exercise Performance of Children Born Non-Extremely Preterm |
| title_fullStr | Cardiopulmonary Exercise Performance of Children Born Non-Extremely Preterm |
| title_full_unstemmed | Cardiopulmonary Exercise Performance of Children Born Non-Extremely Preterm |
| title_short | Cardiopulmonary Exercise Performance of Children Born Non-Extremely Preterm |
| title_sort | cardiopulmonary exercise performance of children born non extremely preterm |
| topic | cardiopulmonary exercise testing exercise performance exercise tolerance prematurity preterm children children |
| url | https://www.mdpi.com/2227-9067/11/2/198 |
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