High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos

High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos

Summary Recently, gene editing with transcription activator-like effector nucleases (TALENs) has been used in the life sciences. TALENs can be easily customized to recognize a specific DNA sequence and efficiently introduce double-strand breaks at the targeted genomic locus. Subsequent non-homologou...

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Bibliographic Details
Main Authors:	Ken-ichi T. Suzuki, Yukiko Isoyama, Keiko Kashiwagi, Tetsushi Sakuma, Hiroshi Ochiai, Naoaki Sakamoto, Nobuaki Furuno, Akihiko Kashiwagi, Takashi Yamamoto
Format:	Article
Language:	English
Published:	The Company of Biologists 2013-03-01
Series:	Biology Open
Subjects:	Eye Pax6 Pigmentation TALEN Tyrosinase Xenopus laevis
Online Access:	http://bio.biologists.org/content/2/5/448

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