Vascular ageing: A relationship between vascular stiffness and erythropoietin among different age groups of male and female participants
Background: The blood pressure, pulse wave velocity (PWV) and arterial stiffness index (ASI) are important markers for age related alterations of vascular function. Further a link between vascular stiffness and erythropoietin are least explored in relation to sex and age. Objective: The present stud...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2020-01-01
|
| Series: | BLDE University Journal of Health Sciences |
| Subjects: | |
| Online Access: | http://www.bldeujournalhs.in/article.asp?issn=2468-838X;year=2020;volume=5;issue=3;spage=41;epage=42;aulast=Khodnapur;type=0 |
| _version_ | 1818871039944294400 |
|---|---|
| author | Jyoti Khodnapur Kusal K Das |
| author_facet | Jyoti Khodnapur Kusal K Das |
| author_sort | Jyoti Khodnapur |
| collection | DOAJ |
| description | Background: The blood pressure, pulse wave velocity (PWV) and arterial stiffness index (ASI) are important markers for age related alterations of vascular function. Further a link between vascular stiffness and erythropoietin are least explored in relation to sex and age.
Objective: The present study was aimed to assess the vascular health in relation to ageing with special reference to erythropoietin in both male and female.
Methods: 204 healthy male (n= 102) and female (n=102) participants (20 to 95 years) were randomly selected among general population of Vijayapur city, Karnataka. Participants were divided into group I (20-29years), II (30-39 years), III (40-49 years), IV (50-59 years), V (60-69 years) and VI (>70 years). Physical anthropometry, physiological parameters, hematology and serum erythropoietin (Epo) were assessed. Vascular stiffness indicators like PWV (b-a PWV and c-f PWV) and ASI (brachial ASI and ankle ASI) were also evaluated. Statistical analysis was performed by using one way ANOVA and post hoc test by using SPSS software.
Results: Increase of MAP, PWV and ASI along with concomitant decrease of serum Epo were observed in group V and VI of both males and females. While comparing between male and female all the vascular parameters showed significant differences in group I to IV only.
Conclusion: The present study clearly showed impact of ageing on PWV, ASI, MAP and Epo in higher age groups of males and females. Epo is sensitive in older age groups in relation to vascular functions. |
| first_indexed | 2024-12-19T12:16:35Z |
| format | Article |
| id | doaj.art-4921d123fbbe4127af1a1a37e9904416 |
| institution | Directory Open Access Journal |
| issn | 2468-838X 2456-1975 |
| language | English |
| last_indexed | 2024-12-19T12:16:35Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | BLDE University Journal of Health Sciences |
| spelling | doaj.art-4921d123fbbe4127af1a1a37e99044162022-12-21T20:21:57ZengWolters Kluwer Medknow PublicationsBLDE University Journal of Health Sciences2468-838X2456-19752020-01-0153414210.4103/2468-838X.303798Vascular ageing: A relationship between vascular stiffness and erythropoietin among different age groups of male and female participantsJyoti KhodnapurKusal K DasBackground: The blood pressure, pulse wave velocity (PWV) and arterial stiffness index (ASI) are important markers for age related alterations of vascular function. Further a link between vascular stiffness and erythropoietin are least explored in relation to sex and age. Objective: The present study was aimed to assess the vascular health in relation to ageing with special reference to erythropoietin in both male and female. Methods: 204 healthy male (n= 102) and female (n=102) participants (20 to 95 years) were randomly selected among general population of Vijayapur city, Karnataka. Participants were divided into group I (20-29years), II (30-39 years), III (40-49 years), IV (50-59 years), V (60-69 years) and VI (>70 years). Physical anthropometry, physiological parameters, hematology and serum erythropoietin (Epo) were assessed. Vascular stiffness indicators like PWV (b-a PWV and c-f PWV) and ASI (brachial ASI and ankle ASI) were also evaluated. Statistical analysis was performed by using one way ANOVA and post hoc test by using SPSS software. Results: Increase of MAP, PWV and ASI along with concomitant decrease of serum Epo were observed in group V and VI of both males and females. While comparing between male and female all the vascular parameters showed significant differences in group I to IV only. Conclusion: The present study clearly showed impact of ageing on PWV, ASI, MAP and Epo in higher age groups of males and females. Epo is sensitive in older age groups in relation to vascular functions.http://www.bldeujournalhs.in/article.asp?issn=2468-838X;year=2020;volume=5;issue=3;spage=41;epage=42;aulast=Khodnapur;type=0ageingpulse wave velocityarterial stiffness indexvascular healtherythropoietin |
| spellingShingle | Jyoti Khodnapur Kusal K Das Vascular ageing: A relationship between vascular stiffness and erythropoietin among different age groups of male and female participants BLDE University Journal of Health Sciences ageing pulse wave velocity arterial stiffness index vascular health erythropoietin |
| title | Vascular ageing: A relationship between vascular stiffness and erythropoietin among different age groups of male and female participants |
| title_full | Vascular ageing: A relationship between vascular stiffness and erythropoietin among different age groups of male and female participants |
| title_fullStr | Vascular ageing: A relationship between vascular stiffness and erythropoietin among different age groups of male and female participants |
| title_full_unstemmed | Vascular ageing: A relationship between vascular stiffness and erythropoietin among different age groups of male and female participants |
| title_short | Vascular ageing: A relationship between vascular stiffness and erythropoietin among different age groups of male and female participants |
| title_sort | vascular ageing a relationship between vascular stiffness and erythropoietin among different age groups of male and female participants |
| topic | ageing pulse wave velocity arterial stiffness index vascular health erythropoietin |
| url | http://www.bldeujournalhs.in/article.asp?issn=2468-838X;year=2020;volume=5;issue=3;spage=41;epage=42;aulast=Khodnapur;type=0 |
| work_keys_str_mv | AT jyotikhodnapur vascularageingarelationshipbetweenvascularstiffnessanderythropoietinamongdifferentagegroupsofmaleandfemaleparticipants AT kusalkdas vascularageingarelationshipbetweenvascularstiffnessanderythropoietinamongdifferentagegroupsofmaleandfemaleparticipants |