Functional Diversification of Oyster Big Defensins Generates Antimicrobial Specificity and Synergy against Members of the Microbiota

Functional Diversification of Oyster Big Defensins Generates Antimicrobial Specificity and Synergy against Members of the Microbiota

Big defensins are two-domain antimicrobial peptides (AMPs) that have highly diversified in mollusks. <i>Cg</i>-BigDefs are expressed by immune cells in the oyster <i>Crassostrea gigas</i>, and their expression is dampened during the Pacific Oyster Mortality Syndrome (POMS), w...

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Bibliographic Details
Main Authors: Noémie De San Nicolas, Aromal Asokan, Rafael D. Rosa, Sébastien N. Voisin, Marie-Agnès Travers, Gustavo Rocha, Luc Dantan, Yann Dorant, Guillaume Mitta, Bruno Petton, Guillaume M. Charrière, Jean-Michel Escoubas, Viviane Boulo, Juliette Pouzadoux, Hervé Meudal, Karine Loth, Vincent Aucagne, Agnès F. Delmas, Philippe Bulet, Caroline Montagnani, Delphine Destoumieux-Garzón
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Marine Drugs
Subjects:
antibacterial peptide
beta defensin
diversity
evolution
microbiome
invertebrate
Online Access:https://www.mdpi.com/1660-3397/20/12/745

Internet

https://www.mdpi.com/1660-3397/20/12/745

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