Prioritization and functional validation of target genes from single-cell transcriptomics studies
Abstract Translation of academic results into clinical practice is a formidable unmet medical need. Single-cell RNA-sequencing (scRNA-seq) studies generate long descriptive ranks of markers with predicted biological function, but without functional validation, it remains challenging to know which ma...
Main Authors: | Liliana Sokol, Anne Cuypers, Anh-Co K. Truong, Ann Bouché, Katleen Brepoels, Joris Souffreau, Katerina Rohlenova, Stefan Vinckier, Luc Schoonjans, Guy Eelen, Mieke Dewerchin, Laura P.M.H. de Rooij, Peter Carmeliet |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-06-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-023-05006-7 |
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