The long-term prognostic value of E/e’ in patients with ST segment elevation myocardial infarction
Objectives: This study aimed to evaluate the long-term prognostic value of E/e’ ratio in patients with ST-segment elevation myocardial infarction (STEMI). Methods: We retrospectively assessed 314 patients who underwent primary coronary interventions between January 2010 and December 2015. The includ...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Indian Heart Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0019483222001146 |
| _version_ | 1828201237422538752 |
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| author | Jino Park Yeo-Jeong Song Seunghwan Kim Dong-Kie Kim Ki-Hun Kim Sang-Hoon Seol Doo-Il Kim Sang-Jin Ha |
| author_facet | Jino Park Yeo-Jeong Song Seunghwan Kim Dong-Kie Kim Ki-Hun Kim Sang-Hoon Seol Doo-Il Kim Sang-Jin Ha |
| author_sort | Jino Park |
| collection | DOAJ |
| description | Objectives: This study aimed to evaluate the long-term prognostic value of E/e’ ratio in patients with ST-segment elevation myocardial infarction (STEMI). Methods: We retrospectively assessed 314 patients who underwent primary coronary interventions between January 2010 and December 2015. The included patients were classified into two groups according to the E/e’ ratios: E/e’<15 (n = 245) and E/e’≥15 (n = 69). We investigated the incidence of major adverse cardiac events (MACEs) from the event to the final follow-up period of at least three years. Results: A total of 55 cases of MACEs occurred during the follow-up. The E/e’≥15 group showed a significantly higher rate of MACEs than the E/e’<15 group (34.8% vs. 12.7%, p < 0.001). Among the MACE, the percentage of cardiac deaths (17.4% vs. 0.4%, p < 0.001) was higher in the E/e’≥15 group than in the E/e’<15 group. In the multivariable model, E/e’≥15 was demonstrated as the strongest prognostic factor for MACEs (hazard ratio [HR], 2.597; 95% confidence interval [CI], 1.294–5.211; p = 0.007) and cardiac death (HR, 27.537; 95% CI, 3.287–230.689; p = 0.002), while left ventricular ejection fraction (LVEF) was not. Neither the discrepancy of systolic nor diastolic function between initial and follow-up echocardiography affected the overall prevalence of MACEs. A disparity was observed between the two groups, with a significant increase in the rate of MACEs in the E/e’≥15 group (log-rank test, p < 0.001). Conclusion: The baseline E/e’≥15 in patients with STEMI after successful reperfusion is the strongest predictor of poor long-term clinical outcomes among those analyzed. |
| first_indexed | 2024-04-12T11:26:22Z |
| format | Article |
| id | doaj.art-492749baf14a43b683c5eb368b924b99 |
| institution | Directory Open Access Journal |
| issn | 0019-4832 |
| language | English |
| last_indexed | 2024-04-12T11:26:22Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Indian Heart Journal |
| spelling | doaj.art-492749baf14a43b683c5eb368b924b992022-12-22T03:35:13ZengElsevierIndian Heart Journal0019-48322022-09-01745369374The long-term prognostic value of E/e’ in patients with ST segment elevation myocardial infarctionJino Park0Yeo-Jeong Song1Seunghwan Kim2Dong-Kie Kim3Ki-Hun Kim4Sang-Hoon Seol5Doo-Il Kim6Sang-Jin Ha7Department of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of KoreaDepartment of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea; Corresponding author. Department of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine 875, Haeun-daero, Haeundae-gu, Busan, 48108, Republic of Korea.Department of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of KoreaDepartment of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of KoreaDepartment of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of KoreaDepartment of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of KoreaDepartment of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of KoreaDepartment of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Republic of KoreaObjectives: This study aimed to evaluate the long-term prognostic value of E/e’ ratio in patients with ST-segment elevation myocardial infarction (STEMI). Methods: We retrospectively assessed 314 patients who underwent primary coronary interventions between January 2010 and December 2015. The included patients were classified into two groups according to the E/e’ ratios: E/e’<15 (n = 245) and E/e’≥15 (n = 69). We investigated the incidence of major adverse cardiac events (MACEs) from the event to the final follow-up period of at least three years. Results: A total of 55 cases of MACEs occurred during the follow-up. The E/e’≥15 group showed a significantly higher rate of MACEs than the E/e’<15 group (34.8% vs. 12.7%, p < 0.001). Among the MACE, the percentage of cardiac deaths (17.4% vs. 0.4%, p < 0.001) was higher in the E/e’≥15 group than in the E/e’<15 group. In the multivariable model, E/e’≥15 was demonstrated as the strongest prognostic factor for MACEs (hazard ratio [HR], 2.597; 95% confidence interval [CI], 1.294–5.211; p = 0.007) and cardiac death (HR, 27.537; 95% CI, 3.287–230.689; p = 0.002), while left ventricular ejection fraction (LVEF) was not. Neither the discrepancy of systolic nor diastolic function between initial and follow-up echocardiography affected the overall prevalence of MACEs. A disparity was observed between the two groups, with a significant increase in the rate of MACEs in the E/e’≥15 group (log-rank test, p < 0.001). Conclusion: The baseline E/e’≥15 in patients with STEMI after successful reperfusion is the strongest predictor of poor long-term clinical outcomes among those analyzed.http://www.sciencedirect.com/science/article/pii/S0019483222001146E/e’MACEOutcomePrognosisSTEMI |
| spellingShingle | Jino Park Yeo-Jeong Song Seunghwan Kim Dong-Kie Kim Ki-Hun Kim Sang-Hoon Seol Doo-Il Kim Sang-Jin Ha The long-term prognostic value of E/e’ in patients with ST segment elevation myocardial infarction Indian Heart Journal E/e’ MACE Outcome Prognosis STEMI |
| title | The long-term prognostic value of E/e’ in patients with ST segment elevation myocardial infarction |
| title_full | The long-term prognostic value of E/e’ in patients with ST segment elevation myocardial infarction |
| title_fullStr | The long-term prognostic value of E/e’ in patients with ST segment elevation myocardial infarction |
| title_full_unstemmed | The long-term prognostic value of E/e’ in patients with ST segment elevation myocardial infarction |
| title_short | The long-term prognostic value of E/e’ in patients with ST segment elevation myocardial infarction |
| title_sort | long term prognostic value of e e in patients with st segment elevation myocardial infarction |
| topic | E/e’ MACE Outcome Prognosis STEMI |
| url | http://www.sciencedirect.com/science/article/pii/S0019483222001146 |
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