Prognostic value of the combined preoperative plasma fibrinogen and systemic inflammatory indexes in ESCC patients

Abstract The prognostic indexes based on the combination of preoperative fibrinogen and systemic inflammatory indexes may have greater predictive value in esophageal squamous cell carcinoma (ESCC). It was found that the predictive ability of F-NLR was more valuable than other systemic inflammatory i...

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Bibliographic Details
Main Authors: Honggang Cao, Hongtai Shi, Miaomiao Zhao, Zhenhua Liu, Jun Qian
Format: Article
Language:English
Published: Springer 2023-08-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-023-00763-7
Description
Summary:Abstract The prognostic indexes based on the combination of preoperative fibrinogen and systemic inflammatory indexes may have greater predictive value in esophageal squamous cell carcinoma (ESCC). It was found that the predictive ability of F-NLR was more valuable than other systemic inflammatory indexes. The preoperative F-NLR score was closely related to the TNM stage, and could be used as an important independent prognostic index for patients with ESCC. Then the nomogram model constructed by F-NLR and TNM stage had higher prognostic ability than that of AJCC stage for ESCC patients. Preoperative F-NLR is a new independent prognostic index and a potential marker for treatment response monitoring in patients with ESCC.
ISSN:2730-6011