Enteropathogenic E. coli infection co-elicits lysosomal exocytosis and lytic host cell death
ABSTRACTEnteropathogenic Escherichia coli (EPEC) is a primary human enteric bacterial pathogen causing acute diarrhea in children. EPEC colonizes the small intestine, and the disease is induced, in part, by the ability of the pathogen to utilize a type III secretion machinery to inject a battery of...
Main Authors: | Raisa Shtuhin-Rahav, Aaron Olender, Efrat Zlotkin-Rivkin, Etan Amse Bouman, Tsafi Danieli, Yael Nir-Keren, Aryeh M. Weiss, Ipsita Nandi, Benjamin Aroeti |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2023-12-01
|
Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mbio.01979-23 |
Similar Items
-
Topology and function of translocated EspZ
by: Nir Haritan, et al.
Published: (2023-08-01) -
Enteropathogenic Escherichia coli regulates host-cell mitochondrial morphology
by: Jennifer Lising Roxas, et al.
Published: (2022-12-01) -
Attaching-and-Effacing Pathogens Exploit Junction Regulatory Activities of N-WASP and SNX9 to Disrupt the Intestinal Barrier
by: John J. Garber, et al.
Published: (2018-01-01) -
The EspF N-Terminal of Enterohemorrhagic Escherichia coli O157:H7 EDL933w Imparts Stronger Toxicity Effects on HT-29 Cells than the C-Terminal
by: Xiangyu Wang, et al.
Published: (2017-09-01) -
EspH interacts with the host active Bcr related (ABR) protein to suppress RhoGTPases
by: Rachana Pattani Ramachandran, et al.
Published: (2022-12-01)