Unraveling the complex interplay between anti-tumor immune response and autoimmunity mediated by B cells and autoantibodies in the era of anti-checkpoint monoclonal antibody therapies

Unraveling the complex interplay between anti-tumor immune response and autoimmunity mediated by B cells and autoantibodies in the era of anti-checkpoint monoclonal antibody therapies

The intricate relationship between anti-tumor immunity and autoimmunity is a complex yet crucial aspect of cancer biology. Tumor microenvironment often exhibits autoimmune features, a phenomenon that involves natural autoimmunity and the induction of humoral responses against self-antigens during tu...

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Bibliographic Details
Main Authors: Sarah Soussan, Guilhem Pupier, Isabelle Cremer, Pierre-Emmanuel Joubert, Catherine Sautès-Fridman, Wolf Herman Fridman, Sophie Sibéril
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
B cells
autoantibodies
cancer
autoimmunity
immune checkpoints
therapeutic monoclonal antibodies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1343020/full

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