CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever
The extracellular secreted NS1 (sNS1) is a major factor contributing to dengue hemorrhagic fever. Here, Shu et al. report sNS1 exists in multiple oligomeric states and presents a tetrameric structure.
Bibliographic Details
Main Authors: |
Bo Shu,
Justin S. G. Ooi,
Aaron W. K. Tan,
Thiam-Seng Ng,
Wanwisa Dejnirattisai,
Juthathip Mongkolsapaya,
Guntur Fibriansah,
Jian Shi,
Victor A. Kostyuchenko,
Gavin R. Screaton,
Shee-Mei Lok |
Format: | Article
|
Language: | English |
Published: |
Nature Portfolio
2022-11-01
|
Series: | Nature Communications
|
Online Access: | https://doi.org/10.1038/s41467-022-34415-1
|