CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever

CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever

The extracellular secreted NS1 (sNS1) is a major factor contributing to dengue hemorrhagic fever. Here, Shu et al. report sNS1 exists in multiple oligomeric states and presents a tetrameric structure.

Bibliographic Details
Main Authors: Bo Shu, Justin S. G. Ooi, Aaron W. K. Tan, Thiam-Seng Ng, Wanwisa Dejnirattisai, Juthathip Mongkolsapaya, Guntur Fibriansah, Jian Shi, Victor A. Kostyuchenko, Gavin R. Screaton, Shee-Mei Lok
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34415-1

Internet

https://doi.org/10.1038/s41467-022-34415-1

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